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Anovulation can represent an extremely challenging time for women and a lot of questions arise because of this uncertainty. Infertility is a potential consequence, but the duration and the magnitude of this disorder is not the same for each patient. Clomiphene citrate (or Clomid) is one type of preparation that patients can consider when they are trying to reverse their infertility when they are having problems with ovulation. 

This medication is designed to change the hormone balance in women and acts primarily on the hypothalamus and the pituitary gland. Dysfunction along this pathway is a common reason why women may become infertile. Clomid tries to reestablish the balance of hormones during the luteal phase of a woman's menstrual cycle. Unfortunately, when you are dealing with this pathway, there is a delicate balance that must be maintained and either too little or too much of this medication can prevent fertility from occurring. 

In one study done to determine the effectiveness and side effects of this medication, it was determined that patients that took 50 mg of this medication, had the lowest level of the potential side effects, but the clinical effectiveness was not impressive. Doses that were close to 200 mg produced the highest therapeutic response and approximately 70 percent of patients were able to ovulate within 5 days of taking this medication. [1]

Even if there is a lot of upside with this type of medication, there are some potential risks that patients need to consider before they get too excited about this Clomid. 

Women can start to develop a resistance to this medication so it is important for patients not to use it too often. 

It is also possible for patients to have multiple pregnancies when using this medication through a phenomenon called ovarian hyperstimulation. Clomid causes ovaries to secrete too many eggs at one time which can lead to multiple eggs getting fertilized at once. If you are an older woman looking at a potential way to have a child, you may get more than you bargained for if you have twins or even more. 

Not only is this a beneficial medication for women, it is also helpful in males who suffer from infertility. Male infertility is much more common than people think and 50 percent of infertility cases are because of the men entirely, while women can conceive without a problem. Male hypogonadism was one of the most common reasons why male patients were infertile. 

In one experiment done to determine the effectiveness of Clomid on this population, 86 male patients who were suffering from infertility were given this medication. In this study, it was determined that male patients who took as little as 25 mg of Clomid every other day noticed a statistically significant increase in their testosterone and gonadotropin levels. Males also did not report any noticeable side effects that forced them to stop taking the medication. [2] Both of these studies prove that it is possible for patients to find relief for their infertility and be able to conceive. 

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