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I was on Depo- Provera shots for about 3 years. Once going off the shot, I have had excruciating headaches either before, after and or during my cycle every month. Medications that were prescribed have been unsuccessful in treatment. I never had any headaches during the course of treatment, nor before using Depo- Provera shots. I would take every cycle for every year back, in return not to have these terrible headaches.

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I would recommend a blood test, your hormone levels could be off, maybe a short term hormone replacement would help you if so. My estrogen dropped to menopausal levels coming off nuvaring, Liz
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I am experiencing the same headaches coming off of depo for 5 weeks now!!! Have yours stopped yet?
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