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Niaspan 1000 mg............Anyone else on this drug..?
It is used for lowering Cholesterol in the blood. Along with other medications of course. This medication affects me in a way that is extreme, however I have no choice but to keep taking it. The reactions I get from this are a very red face and neck. Hive type reaction on my forearm inners, and a severe burning sensation through out my body. I Take it before going to bed so the reactions are not as severe, now sometimes it awakes me due to the burning sensation. It feels like I am on fire! I get this on and off, I read somewhere that certain foods or juices affect this, but don't remember where I seen it.

So is anyone else on this medication and if so what are your reactions to it, when do you take it and what do you avoid when taking it..?

Thanks for the info, those of you whom wish to submit.

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Avoid grapefruit juice!
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I also take Niaspan and occasionally experience the hot flash/flushing. And you are correct, it sometimes feels like you are on fire. If there is such a thing as spontaneous combustion, this is what it must feel like! I have found that taking it before bed is best. Also, I found that if I exercised within 2 hours of taking the medication it often resulted in the hot skin flushing later on. Consequently I do not exercise within 2 hours of taking the medication.

Taking aspirin (approximately 30 minutes before taking NIASPAN) or a nonsteroidal anti-inflammatory drug (e.g., ibuprofen) may minimize flushing. To avoid ingestion of alcohol or hot drinks around the time of NIASPAN administration, to minimize flushing.


The manufacturer has reformulated Niaspan to reduce the flushing tendancy. You can tell if you have the reformulated pills by the color. The old formulation was white. The new formulation is orange.

Oh, and Niaspan is primarily prescribed to increase high density lipids (HDL), which are the good cholesterols.
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I had the same flushing issue with out-of-control scratching. My cardiologist recommended taking aspirin 81mg 30 minutes prior to taking the Niaspan (1500mg) prior to bedtime. She stated i could take up to 324mg of aspirin if needed, but the 81mg did the trick. Hope this helps.
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If you are taking Niaspan, do three things (two already mentioned):
1) Take it before you go to sleep at night.
2) Take it 15-30 minutes after you take one or two baby aspirin.
3) Take it at the same time you have a small cup of apple sauce. The pectin in the apple sauce mitigates the Niaspan side effects.

Also, remember that the side effects gradually decrease over time. The first few days or weeks can be torture, but you body will build up a tolerance.
Meanwhile, avoid any fatty foods or alcohol a couple hours before you take Niaspan. I've been on Niaspan for several months and outside of occasional itching on my neck, I've been fine. I believe the apple sauce goes a long way in curbing the flushing and itching.
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I was told by my doctor to take an aspirin about 20 min before taking the niaspan.  Then eat dried apricots or a small cup of applesauce before taking it. (I do both ). Take it before going to bed.  I have not had any of the flushing side effects while following this procedure.
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I take 1000mg of niaspan 3 times a day as directed by my doctor. I have been taking it for almost 6 months. I also experienced the sever hot itching (I call it flushing). I never take it without some kind of food (usually toast or banana) & some milk. I recently decided to cut out some of the foods I eat, 1 at a time, for a while, and see if any of them affected or reduced the flushing. First thing I stopped eating is sweets (need to anyway for better health) so that is where I started. I have not had any sweets (deserts, ice cream, candy, etc) now for 2 weeks and I have also had absolutely NO flushing. Got to wonder about it.
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I was put on this medicine, had been on it for three days. I took it at night with a baby aspirin and a small snack. The last time I took it, I woke up 2 hours later with the feeling of hot acid being thrown on me, all over my torso, back arms face, and neck. My face and arms started swelling, and my face went numb. My husband took me to the ER and they had to start me on a beta blocker, Benadryl, and some other meds through IV. They told me I had a severe allergic reaction to it, and I was to stop taking it immediately. They sent me home on prednisone, and an anti itch medicine.

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I was in US and was using Niaspan 2000mg for the last 2 years. I moved back to India and here Niaspan is unavailable. Instead, there is Nialip available. Are there any issues in replacing Niaspan with Nialip?
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