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:-D HI EVERYONE! IM SO THANKFUL FOR EVERYONE BEING SO OPEN, AN CANDID ABOUT THE CERTAIN HELLS THAT THEY ARE GOING THREW. IT BREAKS MY HEART. ONE THING IS STILL TRUE THAT MISERY LOVES COMPANY, AN WE NEED EACHOTHER. IM READING THIS TO UNDERSTAND BETTER THE WITHDRAWALS OF SEROQUEL. I HAVE A LOVE ONE THAT IS SUFFERING FROM IT, IT HAS BEEN 4 MONTHS AN SHE STILL FEELS LIKE HELL. I WOULD SO MUCH LIKE TO KNOW IF SOMEONE HAS DONT THIS, WHAT DID THEY DO TO FEEL BETTER WHILE GOING THREW THIS?. OR ANY ADVICE THAT WOULD HELP. GOD HELP US ALL, MY VERY BEST HEARTFELT PRAYERS FOR US ALL
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I started taking 5-HT (5 hydroxytryptophan) Precursor to Serotonin... when I stopped Seroquel (the WORST drug I have ever taken)
Seroquel lowers serotonin (and dopamine) in the brain.
***edited by moderator*** web addresses not allowed

Strange that 1 of its uses is for (atypical) depression since SSRI's (Selective serotonin reuptake inhibitors) are used for depression (the SSRI's INCREASE serotonin).

It takes time for Seroquel to have its "positive" effects on schizophrenia and (atypical) depression so it should theoretically take time (I have heard up to 6 months) for it to wear off.
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Question and Reply

I was on Seroquel for sleep from May - December 26, 2010 (25 - 50 mg. at night). Stopped "cold" 12/26/10. Had horrible side effects.

I did not have major withdrawals and was so relieved to have stopped the WORST drug I have ever been on. (25-50 mg is low but it would knock me out and had the devastating side effects.)

I have been off the garbage for 3 months but 2 weeks ago got SEVERE muscle / bone / joint pain. I cannot walk and in so much pain I cannot even get to my doctor.
Also swollen ankles.
(I have not started or changed any medications since stopping Seroquel except I had started taking 5-HT (5-hydroxytryptophan - serotonin precursor) 1 week after stopping Seroquel.

Could the muscle / bone / joint pain and swelling be a late withdrawal reaction?
If so, please let this post be a warning to people.

As far as advice: It takes time for Seroquel to have "positive" effects on schizophrenia and atypical depression. (I cannot find the amount of time anywhere) but the "benefits" are not immediate. I have heard (read) that it can take up to 6 months for it to leave ones system
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I have been on Seroquel for 5 years the dosage was changed again and again. Withdrawal pure hell! All I felt like doing was curling up into a fetus position. I have recently noticed tremors and hand skaking to the point I can't hardly write or hold things. I have had it with this drug! What ever you do I would not suggest cold turkey. Let the Doctor taper you off of them that way the side effects will not be quite as bad. I have missed a dose several days and could not sleep at all. I am angry, agitated, hostile, fits of rage, not sure what is going on but I want of the seroquel. It can work fine for some people but some of us not so good. There is also a lawsuit against this drug currently in effect. Hope this information helps someone else that maybe having the same problems.
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I am on 1000 seroquel a day and cant sleep. i will fight this but will it get better sex life sucks thats why i want out
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Hey, i've been trying to get off seroquel, went through hell. I was on 200mg, now trying to stay on 100mg, don't know if i'll be able to do it. I think I went to fast. If anyone wants to get of meds, he needs to do slowly, sometimes it may take a year to get off. Don't mess with your brain, this medication is very addictive. Reduce, for example, by 10mg each month or more, don't reduce by another 10mg untill you went through the entire withdrawal from the first 10mg. A lot of docs will try to get you off from meds very fast, and if you go through pain, they don't care, it's not them who suffering but you. I was in a hurry to get off because of side effects, first month i felt fine, because of that I was reducing more and more, then the hell started, almost ended up in the mental hospital that I find addictive as well. So I went up from 50mg to 150mg. Remember, if you try to get off fast, you are screwing with your brain. We're all different, some people are sicker and others, and it takes longer for them to adapt to being without medication. Also, you might not be ready yet. Do therapy and 12 step programs, if you have no tools to cope with stress, how are you planning to deal with every day stresses without your medication.
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Hey everyone.



I'm not sure how long i've been taking seroquel for.. maybe four- five years for Bipolar Disorder. I've been on meds for Bipolar since i was 13... so 7 years. Seroquel so far has been the best drug i've been on.

i'm on a fairly low dose atm, 400 mg (i no longer take anything else). 

I'm currently fed up with the side effects. 

I take them and my nose blocks up- 

my heart feels like it stops

i often wake up paralysed and witness vivid visual hallucinations  (people with dead animals on their head)

i have intense falling sensations almost every minute

I feel like my brain is exploding

i have sensory hallucinations like my lips feeling furry. 

I often enter a half sleep- where i'm so stoned on the drugs that my brain is kind of shut down but i'm still awake, but kind of forget that my eyes are open.

peeling tongue- white on the top 


I'm sick of describing the indescribable side effect sensations i have in my drugged/sleep haze to my doctor, or my mum when i wake her up at 4 am in my panic. 

They're always so obscure- the sideffects.. and the same kind of thing-weird feelings in my body or head.. but they feel different enough each night for me to feel there's a cause for concern.

ENOUGH!

I've gone cold turkey for a day or two maybe 5 times. 

Things i experienced in 60 hour periods.

* sleep impossible

* intense stomach cramps

* Talking about three times as fast

* Mania each time- racing thoughts, happiness/bliss, ideas 


I'm very inclined to go cold turkey and push through all these horrors but i've decided to wean off the seroquel slowly to nothing- i can't imagine it's healthy to go cold turkey and whats a couple more months on 7 years?

I'm almost certain that when numb bland me leaves with the meds bipolar-anxious-delusional me of the past will come back but i want to be entirely certain that being on no medication is a non option.. i'm 20 now and i started meds when i was 13 so on the other side of puberty things might be different.. i hope!

i'll post here if i can to let you know how it goes.. 

This is at no detriment to my psychiatrist whose been wonderful.. when i'm not suffering side effects i'm very stable and more normal than most mentally unscathed people.. this is a personal adventure i'm sure most bipolarbears take.



If anyone is experiencing any of my side effects which seem to be unheard of when i search the net please reply to me, i'd love to talk to someone.




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Hi im taking seroquel for scitsofrenia im trying to get off of it doctors want let me and i cant sleep with out them but i am down to fifty milagrams indtead of four hundred also taking clanazapan is there any way i can get off of them completely
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Quetiapine Fumerate (Seroquel) is an evil, nasty drug!

Do not go off of it cold turkey, it can cause terrible withdrawal physical symptoms, like irregular heart beat, low blood pressure, myocardial infarction - cardiac arrest, seizures and death.

Medical doctors say Seroquel is not addictive, but the fact is they are too retarded to notice that it is not an anti psychotic, they DID NOT test this drug thoroughly, it should not have been FDA approved, it is a highly addictive sleeping pill gone insane, there is not enough research, they don't even know how it effects the brain, it has worse and similar symptoms to street drugs, and the terrible physical symptoms are enough to fill 10 novels. New reports are now saying Seroquel is now being changed as "not an anti psychotic" but more of a sleeping pill, that may or may not help with impulse and moods. However one of the thousands of symptoms, is of course, suicidal tendencies, impulsiveness and unstable moods.

They originally put me on 900mgs. I have been weaning off of them for several years - it is an awfully long process. Every drop and lower in dosage proves to create more terrible drug induced symptoms.
You CANNOT go off of seroquel cold turkey, especially if you have been on it for as many years as I have. If I even try to, I cannot last more than a day without severe medical symptoms.

Last new years eve, I stayed up all night and refused to take my meds. Why? Because the reliance my body has on them for sleep is annoying. And unnatural. It interferes with my life. They are some of the worst sleeping pills you can ever take - and they are HIGHLY ADDICTIVE, not in a mental way, but they make your body completely reliant on them for sleep. 
Therefore weaning off, or even going off cold turkey - you will have extreme drug induced insomnia. That is what seroquel does. It makes you unable to sleep without it. 
But that's not all. 
The thing with Seroquel is it really messes up everything to do with your sleep patterns. That means after taking it for several years of being on it, it would force me to pass out for exactly 12 hours. It took maybe an hour or so for it to kick in, but once it does, it makes you pass out. 
If I ever tried to wake up before that 12 hours, I would have worse physical symptoms than ever recorded. I experienced seizures, heart problems, very nasty symptoms, before i would hit the floor and faint.  This means Seroquel actually gives you an unnatural need for more sleep. If you don't get enough sleep = terrible symptoms even possible death. 

If you don't notice hardcore withdrawal symptoms right away, after not taking it for 10 hours, you are lucky. Because for me, even if I forgot taking my meds for 3 hours, I would become disorientated, dizzy, nausea, shaking, break out in terrible sweats, lose control of my muscles. 
And don't forget Bruxism = lock jaw feeling, feeling as if your whole jaw is being squeezed by invisible pliars, and like you can't stop yourself from biting your own tongue. This is commonly a symptom of hardcore drug use seen in abusing ecstacy. That's why you see people who are on ecstacy biting down on baby soothers, and eating lots of rock hard candy. But it's very common with Quietiapine. And it's very unpleasant. And guess what? You might be surprised to know Bruxism is also a sleep disorder condition = how seroquel is entwined with sleep patterns. 
The sad thing is, for people who have had a long time exposure with Seroquel - they might develop long lasting muscle tension, or even long lasting Bruxism.  
But when they say NMS - that is a very serious and fatal thing that can cause death. 
And don't forget blurry vision.

Thank god this last wean down has decreased my appetite! I finally feel as if i have a normal relationship with food again.

I just weaned down to 50mgs from 100 mgs, and it is the worst withdrawals i have ever experienced. See, that isn't even a huge drop, but Seroquel is nasty. No energy, no strength, can't do anything. Thankfully, no psychotic symptoms whatsoever - in the past it would have been different, but this drop down has only resulted in physical withdrawals symptoms. Well, unless you count the one day my moods were all over the place, other than that, it's all been horrible physical ailments. 
 What's really disgusting is the sweats, changes in temperature. I can be sitting in one spot doing nothing, and i break out in this really disgusting body sweat, and it has a very rancid smell. I am really starting to despise the lock jaw feeling. While I was on higher dosages of seroquel, I always twitched and my hands were always shaky - that has actually gotten a little better now, but now i'm experiencing weird muscle tension. In the last few days the nausea has gotten better. But i still feel an overal gross feeling.   

I am happy to report though, that over the years of dropping down from 900mgs, the periods of sleep i was reliant on dropped down. Being on 100mgs was the first time I ever experienced somewhat of a normal sleep schedule, for example I could actually wake up before 12 hours of sleep and not die, i could function okay, but it still took me literally 5 hours in the mornings to wake up fully. Being on 100mgs for a year or longer I was able to experience only having 6 hours of sleep and being able to function okay the next day. There was also this one time, I forgot to get my meds filled, and so i was left for the night without being able to sleep. in the past it was drug induced impossible to sleep without them, but i managed to fall into a sleep through a meditation. However, the sleep was cold, restless, empty and I woke up feeling worse with terribly withdrawal symptoms. 
However, being on 50mgs for a week, was quite a change for the sleep. At first, the meds didn't even kick in, and i experienced my first nights in the history of being on Seroquel that it did not make me pass out. Therefore i had insomnia, though at the time I thought it was mighty cool that i could actually stay awake having taken them. Finally my body adjusted in another weeks time, and sadly... my sleep is back to needing 12 hours of sleep, sometimes more. First days of weaning off - wildy intoxicated, but it was a good trip, talked to myself a lot, had to curve my impulses to talk about obscene sexual things, laughed at everything i saw, very good time. Thankfully that is over. Now, I'm still wildly disorientated, for example if I close my eyes when I am standing, and I open them, I fall over, no balance. 

Long story short - it is not advised to go off of them cold turkey. It is painful, but even weaning off of them slowly has terrible withdrawal symptoms, I don't want to know what it would be like if i just cut them out completely, i'm sure i would not be alive, actually I am certain of that, i nearly died all the times I tried going off of them cold turkey. I was always forced to take the pills because of the symptoms. It will probably take me another year or two to get off of them completely. I've been on them since i was 14, I am now 23. 
Typically, you are supposed to stay on a dosage for at least 6 months before weaning down another quarter or half. To prevent things like death that is. 

But yeah, you don't need quetiapine fumerate, it's a chemical byproduct of nuclear weaponry, just like hydroflouric acid, and the rat poison they put in prozac, if you don't know what's in it, don't take it. All these medications do is make people worse, granted, they think they stumble across these discoveries to help mankind, but sometimes it makes you think if they are intentionally trying to kill us all. And tell me again, why exactly would medical professionals prescribe a medication that causes seizures, or death? Because they are uninformed.

Just like flouride put in our water supplies, it is NOT the trace edible element flourine, it is modified to be an unedible element with traces of things like concrete, hydroflouric acid is not flourine. Flourine is a gas, and in it's edible state it is good for bones and teeth. But the stuff they are creating is certainly not the edible kind of flourine, and is the same stuff you find in rat poisons and insecticides. It's what is making people sick, mentally and physically.  

Chemicals are NOT meant to be filtered by our livers, and once the bodies waste systems are compromised, it causes mental and physical disease. Obviously. 


  
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I'm just miserable I itch sooooo bad! From head to toe and it just keeps moving around. I'm scratching myself almost raw! This is terrible but I refuse to go back on it because I absolutely despise the drug. I'll put up with the itching and hope it goes away soon. Think I'll try some benadryl tonight and see if that helps.
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hey susan im jay i was just having a read of what you have put up and found it intresting.I have only just recently started taking seroquel and i know that things are not right,i feel my brain is all over the place i feel that when i talk its not me talking and when i go from my lounge room to the kitchen i lose those four seconds of time,if u get this or anyone on here that understand how i feel i would love to chat to them i really am in need of serious help and i dont know what to do.My number is 0421 465 458 if u have the time to call me and have a chat about more of your expierences that would be great thanks
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Have just stopped cold turkey due to massive weight gain. I was on 200mg at night. I'm shacky, hot and cold sweats, nausea, but determined to keep going. its been one week so far, and have read I have at least another week of this before I start to improve. I feel like sh*t but I know its worth it.
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I also am having hot flashes then freezing...i wake up, when i do sleep, in cold sweats...im coming off of 300 mg of seroquel...its pure hell..my stomach hurts..i dont feel like myself either..i feel "cracked out"..or something. Im not gonna give up either..i hope. Stay strong! i will if you will.
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I've been on 600 Seroquel. Some instant release and some slow release. for about a year now. I've asked my doctor if I can stop taking it now because I've put on 15 kilos and I sleep 13 hours a day on weekends and am frequently late to work. So I have been gradually winding down the seroquel whilst taking a new drug, Saphris to treat my Bipolar symptoms. Ufortunately, the side effects have been unbearable:


Grinding and clenching teeth

irritable

fidgetting or dyskinesia

squinting my eyes

so anxious I want to scream


Fortunately I am doing a DBT therapy at the moment which has been a great help. Mindfulness meditation always helps my symptoms. So I understand your symptoms, and thank you for describing them so well. I'm glad I'm not the only one having weird, indescribable withdrawal symptoms
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St. Johns Wort and Jesus, that's the only I answer I have!

Prayer can get you through anything.
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