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I have been having issues with my thyroid for as long as i can remember. I have been slowly increasing the level of thyroxine iam taking and am now up to 300 mcg a day. Even with this still having problems. I have irregular vaginal bleeding that has lasted off and on for 2 months now. can not loose weight, tiredness but can not get to sleep, alway feeling im about to get sick to list a few. Any ideas on what i can try or tests to find out.

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It is possible that you are taking way too much thyroid at this point. Your lack of sleep and always feeling like you are getting sick particularly suggest this. Not everyone loses weight when thyroid is up -- some gain because of change in appetite. I suggest you see an endocrinologist before you kill yourself!
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