1st time i have had a yeast infection and thought i was going to go crazy from the crazy itching and burning. Could not get a quick appt so i decided to try Monistat 1. Warning, I used the insert and @ hr later thought i was going insane from the internal itching and burning.Had a pretty awful night sleep. The wipes amd cream did work for the external itching right away. The next day was a complete turn around. It is working & i feel close to normal again. If i have this happen again, will probably try the 3 day since the 1 day was too strong.