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I was reading about grapefruit & Atenelol. First you said:

"Usually, problem as you reported are treated with combination medicine, which contains Atenolol and Nifedipine. You should know that Atenolol belongs to the group of medicines known as Beta-blockers. Nifedipine belongs to the group of medicines known as Calcium Channel Blockers. The preparation that is made of two of those is available in modified release capsule form. This means the medicine is released slowly over the day to give an even effect. Before taking any medicines, as well as with Atenolol, you should check with your pharmacist which medicines are safe for you to take alongside this medicine. Important fact that someone already told you is that you should not drink grapefruit juice while you are being treated with this medicine. However, only Nifedipine interacts with grapefruit juice, so you should avoid this."

Then you said, don't eat or drink Grapefruit Juice with Atenelol. Very confusing. Why only Nifedipine and now Atenelol. Which is it. - - - - - Yes or no. -----"That is why I think you should take care about this, and avoid and grapefruit and grapefruit juice while you take Atenolol. the levels of sugar in your blood. "

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Nifedipin is the one that interacts with grapefruit juice, and not atenolol. Grapefruit juice has the reputation of risky food, because can increase bioavailability of some drugs, especially drugs that are used in treatment of cardiovascular diseases. As it interacts with nifedipin, it also increases absorption of amiodaron, atorvastatin, verapamil, but also carbamazepin, terfenadine, diazepam etc. this list is not complete. This interaction is based on inhibition of enzyme that is responsible for metabolism of these drugs. Pomegranate juice, Seville orange and star fruit juice also should be avoided in therapy with these drugs. As the interaction happens in intestine, only drugs that are orally administrated interact, and not parenterally administered.
There are drugs that are formulated to contain both atenolol and nifedipin in one tablet and are used in treatment of high blood pressure and angina pectoris, like nilol. So, although it is not reported that atenolol interacts with grapefruit, it should be avoided anyway because of nifedipine that interacts.
Recently I have read about new study that has shown that orange juice moderately interacts with atenolol when taken orally. There I read that there has to be interval of at least two hours between taking this drug and orange juice.
Hope that helped.
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