Scientists from the University of Buckingham are trying to introduce a baby formula that would contain leptin in order to chemically restructure children's metabolic system so they wouldn’t become obese.

Leptin is the appetite-controlling hormone that has been found to permanently prevent excess weight gain in mice. The scientists believe it would have the same effects on humans and that it could help decrease the incidence of type 2 diabetes.

It is certain that introducing a leptin-enriched baby milk would raise a lot of medical, legal and ethical questions and there is also a question of whether people would put their children forward for trials of the formula when they do not know the risks involved.

Last years the scientist showed that high doses in mice through pregnancy and early life permanently reduced weight and this is why they believe that leptin plays a role in hard-wiring the brain's appetite response in infancy.
Earlier experiments in treating obese people with leptin didn’t work out because people continued to overeat. And though some research has linked bottle feeding to childhood obesity, none has concluded that breast-fed babies resist obesity throughout life.

Since leptin easily gets destroyed by stomach acids, somo scientists wonder how they think they would get it ingested through baby milk. The led researcher, Professor Cawthorne, said that said babies could ingest leptin because their digestive systems were less developed.

This work is being funded by a government research council and a private individual with no links to industry.