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Scientists found that variant of tumor suppressor gene can be linked with an increased risk of developing aggressive prostate cancer. It was discovered that prostate cancer has a genetic component and this finding pointed that some genetic variants can predispose men to develop prostate cancer.

Scientists examined if genetic changes to SNPs (single nucleotide polymorphisms) can be associated with development of prostate cancer among men with or without this disease. SNPs that were associated with prostate cancer were tested later among men who were treated or screened for prostate cancer.

Researchers found seven SNPs related to development of prostate cancer and after testing they confirmed that one SNPs that’s located in DAB2IP gene which is already proven to be a tumor suppressor gene was related to development of aggressive prostate cancer.

This study is the first one that links genetic changes to prostate cancer but more research needs to be done so it can be proven with strong evidences. Researchers need to find more facts that gene has strong initial statistical support as a tumor suppressor gene. Some others study support the biological role of this gene in development of aggressive prostate cancer.

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Research suggests that men who are at risk for prostate cancer (those who have a family history of the disease or who are of African descent, in particular) may benefit from supplements containing natural extracts of sang huang mushroom and African plum tree bark. These ingredients have demonstrated tumor-shrinking properties in laboratory tests with live mice.

-Alex, PhD

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