Recent research found that certain cancer cells have invisible cloak which allows them to hide from immune system. During the research it was found that metastatic tumors can be invisible to immune system by help of the chromatin remodeling. This is possible in cases of ovarian, prostate, cervical and partly in breast and lung cancers.

Researchers discovered that in metastatic tumors this chromatin remodeling has ability to change structure of chromosomes and these changes reduce production of MHC I which are receptors who have a function of displaying specific cancer signals that immune system recognizes.

If these signals are not displayed, immune system can not detect cancer cells because they seem “invisible” to them. Because of that immune system can not defend itself and cancer cells freely grow and spread in body. High levels of MHC I loss can be a kind of predictor if tumor is growing rapidly and because of that this research is of great importance. In near future, researchers hope that they will be able to prevent cancer cells to form a kind of invisible cloak and that immune system will be able to recognize them.