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Hi, I've been on antidepressant medications for years, finally settling on Effexor XR 150mg daily for the past 2 years. I also take Hydrocodone 5/500 several daily for chronic pain/migraines. I read a post that I can't find now that stated that there is some hope that antidepressants for major depressive disorder and adjunct Oxycontin can help? Is there any truth to that?
Thank you for the help!!

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Hi there. I am not sure if it is possible for the two to work well together only because the oxycontin is a depressant and a painkiller while effexor is an SSRI so the two wouldn't seem to work in conjunction together. It is possible taht they could but I am not entirely certain. Has anyone else heard anything about this?
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