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Hello! My brother has been diagnosed with hepatitis c, genotype 2. Can anybody tell me what does it mean this genotype 2, and what are the treating options? THx

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Genotypes in hepatitis c represent the variation in the genetic makeup of the virus. There are at least six different genotypes and many more subtypes of HCV exist. The most common are genotypes 1, 2, and 3. People with genotypes 2 and 3 are almost three times more likely to respond to therapy than those with genotype 1. Genotyping also can be used to determine the duration of treatment for many people. For those with genotype 2 or 3, a 24-week course of combination therapy is usually sufficient. There is little difference in the severity of disease or outcome of patients infected with different genotypes. However, patients with genotypes 2 and 3 are more likely to respond to interferon treatment. The FDA has approved two different treatment regimens for chronic hepatitis C: monotherapy (using a single drug, interferon) and combination therapy (using two drugs, interferon and ribavirin). The goal of treatment is sustained response--meaning that the virus is not measurable in the blood after drug therapy is completed. Those who continue to have measurable levels of the virus after treatment are considered non-responders. Relapsers "clear" the virus during therapy or shortly thereafter, but the virus returns after therapy ends. About half of the people who initially respond to monotherapy (interferon alone) relapse.
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