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My test result was 2%. How bad am I? And what kind of disease is it?


Basophils are the least common of the granulocytes, representing about 0.01% to 0.3% of circulating leukocytes (white blood cells).

Basophils appear in many specific kinds of inflammatory reactions, particularly those that cause allergic symptoms. Basophils contain anticoagulant heparin, which prevents blood from clotting too quickly. They also contain the vasodilator histamine, which promotes blood flow to tissues. They can be found in unusually high numbers at sites of exoparasite infection, e.g., ticks. They also appear in tissues where allergic reactions are occurring and probably contribute to the severity of these reactions. Basophils have protein receptors on their cell surface that bind IgE antibody very tightly. It is the bound IgE antibody that confers a selective response of these cells to environmental substances, for example, pollen proteins. Recent studies in mice suggest that basophils may also regulate the behavior of T cells and mediate the magnitude of the secondary immune response.