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I recently read an article (World Magazine, 3-17-07) that Dichloroacetate (DCA) may show promise in killing cancer cells, although it has not yet been tested in human trials.
Is any DCA research going to happen soon? Since I am now close to the end of my metatstatic breast cancer battle (9 years), it is tempting to try it without waiting for medical approval.


Sodium dichloroacetate, or NaDCA (abbreviated as DCA or dichloroacetate) is a

simple molecule. It has neither odor nor color. It is non-toxic and cheap to produce.

Representatives from the University of Alberta (UA) claim that it is possible to
use DCA as a cure for various forms of cancer. One of the professors from the

abovementioned University proved that DCA helps with regression of lung and

breast cancers, as well as brain tumors (among others). The results of the study

may be viewed in the research journal Cancer Cell published by the researchers

from UA (including a cardiologist, Dr. Evangelos Michelakis and Dr. Sebastien


It should be noted that DCA had been used before by men of science and medicine.

It was successfully used in treatment of inborn defects connected with

metabolism. These diseases were reported to have a connection with mitochondria.

It should be noted that for nearly 80 years researchers have known that cancer

has a negative influence on mitochondria, causing them to function abnormally.

For most of this time, however, the most popular claim was that it was not

possible for the mitochondria to function normally after they have been affected

by cancer.

Dr. Michelakis attempted to undermine this thesis and stated that DCA may restore

the destroyed mitochondria to their former state. He hoped that during the tests

DCA could make the mitochondria produce an enzyme, which would help in their

restoration. The results of the tests surpassed his expectations. Dichloroacetate

not only prevented the mitochondria from being devastated, but also decreased the

tumor growth in test tubes and animal models. Unlike a great number of

chemotherapies used nowadays, DCA did not affect healthy tissues.

According to Michelakis, this may happen because DCA targets a process, which may

only be observed in cancer cells. He stressed the fact that Dichloroacetate may

be used as a treatment for several forms of cancer.

Because DCA is a small molecule, it is easier for the body to absorb it.

Therefore, it may be used to treat forms of cancer such as brain cancers, which

are unreachable by commonly used drugs.

It is important to note that DCA has already been tested years ago on both

healthy and sick patients. DCA was marked as relatively non-toxic and therefore

action may be taken to test it on people with cancer.

It is a fact that dichloroacetate cannot be patented, being a small molecule. If

it is released as a drug, it would be cheaper than if it would be patented by a

pharmaceutical company. However, for the same reason it is difficult for Dr.

Michelakis to find sponsors for clinical trials for DCA. He is currently

supported by the Canadian Institutes for Health Research, the Canada Foundation

of Innovation, the Canada Research Chairs program, the Alberta Heritage

Foundation for Medical Research and other private sources. The clinical trials on

humans have already started, however it may not be possible for Dr. Michelakis to

finish them yet, because additional funding is needed.

At the beginning of 2007, doctors from the University of Alberta (UA) led by Dr.

Michelakis described their research in Cancer Cell, a scientific journal. They

used a small molecule, dichloroacetate (DCA) on cancer cells in rats and

discovered that due to restoration of damaged mitochondria, the tumors became

smaller by 70% in three weeks.

It is important to note that DCA is not a drug. It is a molecule and as such

cannot be formally prescribed by a doctor or patented as a drug.

here's an interesting cnn interview:
and news in a Canadian tv

here you can find observation data gathered by Canadian Clinic - Medicor Cancer

Centres durning DCA therapy:
and here are 4 cases treated with DCA:

here's an lymphoma remission story using DCA B1 vitamine protocol:
and here are other remissions:

for more info about dca and other therapies visit:


Hey, Teresa.

Josh gave a lot of great facts about DCA.

Also, it is proven that DCA + Tamoxifen has a synergistic effect on Breast cancer. I just can't find the research paper anywhere but you can find it on google.

If you live in Canada, you can visit Medicor clinics - they will advise which path to use when curing IV stage Breast Cancer, however, if you want - you can get DCA yourself from places like PureDc, Sigma-Aldrich.

Godspeed. Let us know if you need more info.

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