Popular belief that Hormone Replacement Therapy does well to women at the onset of menopause is being denied by new studies.

Around 10, 000 women with an average age of 63 took part in the government's Women's Health Initiative. They were divided into groups; one taking hormone pills another taking placebo. Women who took estrogen reported slightly fewer sleep problems, but slightly worse social functioning than those who didn't but overall there was very little difference between the groups.

Estrogen-progestin pills were shown to increase risk for heart attacks, breast cancer and strokes in postmenopausal women while estrogen-only pills slightly increased an older women's risk of a stroke and possible dementia.
The new results for estrogen-progestin showed that the pills had little effect on older women's overall well-being and quality of life. Several other doctors said that this study cannot be generalized to apply to younger women as all the women in the research were about 10 years past the age when troublesome symptoms such as hot flashes and night sweats which can affect quality of life are most likely to occur.
In another study, estrogen pills reduced troublesome hot flashes in a subgroup of younger study participants but that these women still didn't report a better quality of life than placebo users.