So I was on the Depo shot for nearly 2 years, receiving my last shot in November of 2015. I was due for my most recent shot the last week of January but did not have it due to family planning. I have been experiencing for the past 3 weeks extremely tender, painful, and uncomfortable breasts. It hurts if I touch them or change my clothing to fast, even if i have too much pressure on them when i lay down to go to sleep. Any one else experience anything like this, I know that I am not pregnant and am sure that it is a wave of hormones but want to explore other possibilities. I went on the Nuva Ring on the 1st of February as well.