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Are women whiners who moan about every bit of pain they experience? Are men wimps who collapse as soon as they experience the first symptoms of flu? In short, which sex tolerates pain better?

Women, popular belief has it, tend to tolerate pain better than men. If you're a mother who has ever experienced unmedicated labor, you might find it especially funny to check out some of the videos around the web in which men try labor simulators during which a pain that mimics that of contractions is delivered to guys' abdomens, backs, and thighs. They are, of course, writhing in pain after mere minutes, declaring a new-found appreciation for their mothers.

Are women naturally "better" at pain because they're biologically designed for childbirth? Are they just, as some people say, more stoic about pain because doctors tend to take women less seriously when they are in pain so they have learned to simply suck it up? Or is, perhaps, the idea that women handle pain more easily than men actually false? Let's take a look at what science has to say about that. 

How Does Pain Actually Work?

When our body meets a pain stimulus, that's immediately picked up by nociceptors. Nociceptors are a kind of nerve ending that's found all over the body. They detect all kinds of other stimuli besides pain as well, including temperature and pressure, but don't get activated as easily as some other receptors. Because nociceptors have a higher activation threshold, they essentially let you know that something big, to which you should pay attention, is happening.

Once nociceptors are activated in reaction to a pain stimulus, a bunch of chemicals that travel to the brain are released, and pain will register. 

Research as far back as the 1960s discovered that the brain can and does modulate and alter the nervous system in response to pain, meaning that the brain plays a much more flexible role in pain perception that was previously believed. This is where things get really interesting: it could be that women and men have Differing pain modulation systems, and that the hormone estrogen plays a significant role in how women react to pain.

What Do Patient Reports Say?

Pain is a subjective experience, and therefore rather hard to measure. So how can it be done? One underused but readily available resources is a sea of electronic medical records. One research team from Stanford University decided to make used of these EMTs by looking at pain levels self-reported by 11,000 patients. The patients' pain levels were recorded, but the diagnoses made didn't specifically seek to diagnose pain. You know how doctors often ask you to rate your pain levels on a scale from one to 10? Well, the researchers found that women had higher average pain ratings than men did, especially in cases of acute inflammation. The report actually concluded that "pain in women is underdiagnosed and undertreated". 

Another study, published in 2009, reviewed a body of pain-related research and noted that women take more pain killers, see their doctor for pain-related issues more frequently, and have higher incidences of migraines and back pain. 

Does that mean that women are actually less tolerant to pain than women, then? Interestingly, not necessarily. This is where hormones come in. The study found, for instance, that migraine prevalence is roughly equal among boys and girls pre-puberty, while adult women get migraines much more frequently than adult men. Those women who used hormone replacement therapy after the menopause, and those women who used hormonal contraceptives, were also shown to be at a higher risk of experiencing several types of pain. It may not be that women react differently to the same pain stimuli, but that they are more likely to experience certain kinds of pain.

On the other hand, men are notorious for crumbling completely when they get the flu. Denigratingly dubbed the "man flu", this phenomenon was recently proven to be a science fact — because men's immune systems don't have the benefit of added estrogen, men get worse cases of the flu!

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