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Steatocystoma multiplex is a big name for a rare skin disorder that is benign (not cancerous) in nature. It consists of hamartomatous malformations (again, a big name) that are really just cysts that develop in the hair follicles and sebaceous (oil) glands of the skin. This skin condition is usually inherited, although it may also occur sporadically.

Steatocystoma multiplex is characterized by multiple, small, fluid-filled cysts that may enlarge and form tracts under the skin. They can become inflamed, rupture, and attract bacterial infection. However, they are usually painless and non-tender. People usually seek treatment because they can be disfiguring, and scarring can occur. Medical treatments are given to reduce inflammation, minimize scarring, and avoid the need for surgery.

Treatment for Steatocystoma Multiplex

Steatocystoma suppurativa develops when the cysts are infected and become filled with pus. Treatment involves antimicrobial therapy, which may be combined with incision and drainage to remove the pus. The classic form of treatment includes the use of tetracycline antibiotics, which also have anti-inflammatory effects.

Retinoid-like agents such as isotretinoin (Claravis, Amnesteem, Myorisan, and Sotret) have been found to be effective in some patients. Isotretinoin decreases the growth and size of sebaceous glands and decreases their sebum (oil) production. They also decrease the production of certain leukotrienes, which is responsible for their anti-inflammatory effects. However, in some patients, isotretinoin can cause the condition to flare. Furthermore, recurrence following treatment has also been reported.

Because of the potentially dangerous side effects of isotretinoin therapy, only those physicians who are experienced or trained in its use should prescribe it. They must be registered with the US Food and Drug Administration (FDA) to prescribe, dispense, or take isotretinoin.

Other forms of accepted treatment for steatocystoma multiplex consist of simple needle aspiration to reduce facial scarring, surgical excision, mini-incisions, and carbon dioxide laser ablation, which has the best results. Cryosurgery is associated with limited success because of the potential for residual scarring.

Fluorouracil (5-FU) for Steatocystoma Multiplex?

Fluorouracil (5-FU) is a potent drug used to treat certain cancers. It works by slowing or stopping the growth of cells. Fluorouracil is an antimetabolite drug that interferes with the ability of the abnormal cells to grow in the body.

Topical preparations of 5-FU is usually applied on patients with actinic keratosis or basal cell carcinoma (skin cancer) for several weeks. It causes a painful irritation on the top layer of skin, which becomes inflamed and crusty as abnormal cells die.

Fluorouracil injections, on the other hand, are generally used as chemotherapy, in combination with other drugs, to treat colon cancer, rectal cancer, breast cancer, cancer of the pancreas and stomach, and other types of cancer. Injections are usually administered by a doctor or nurse. Its effects must be monitored because of the possibility of serious side effects associated with treatment.

Steatocystoma multiplex is not cancer and is not life-threatening.

Using a strong drug such as fluorouracil injections, which are usually prescribed for advanced cases of cancer, may have more adverse effects than benefits. Consult your doctor for appropriate treatment of your condition.

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