Scarring is very often an aesthetic problem after both minor and major surgeries. Some persons' skin has the tendency to form big, ugly-shaped scars even after small skin lesions. Therefore, many wound healing and scar healing products have been developed to prevent these complications. Mederma is a skin-care product developed by Merz pharmaceuticals. It is intended for scar treatment, and the manufacturer claims it helps to reduce scars and improve the skin's healing process.
Scar formation is a natural healing process in response to tissue damage. Almost all human tissues have a tendency to form scars, with the exception of some self-regenerative tissues, like the liver and bones.
Scar intensity depends on wound severity. If a wound is superficial, and if its edges are close, scarring will be minimal, as skin cells are capable of proliferating and bridging the gap. However, if a wound is wide and deep, especially if a certain amount of tissue is missing, skin cells are unable to bridge the gap and a large amount of scar tissue is formed to replace normal tissue. Scar tissue is composed of collagen fibers, and its protective properties are about 80% of those of normal skin. Scars do not have skin appendices, such as hair follicles, sweat and sebaceous glands, and they are more susceptible to damage caused by mechanical factors and UV light.
Mederma And Its Effectiveness
The active ingredient of Mederma is extract of the common onion (lat. Allium cepa). Onion extract has traditionally been used for the treatment of many skin conditions, has been shown useful in some cases.
Onion is a source of several biologically active substances, such as thiosulfates, bioflavonoids, and metalloproteinases. In some studies, it has been shown to promote wound healing and reduce scaring. Manufacturers of Mederma claim that the appearance of new surgical scars can be significantly improved after applied 3 times daily for 2-3 months. Results of scientific studies were satisfying in general, but the only randomized controlled, single-blind study was conducted in cooperation with Merz, so there is a risk of bias.
Side Effects and Safety of Mederma
Mederma is usually well tolerated. In one study, 6 of 44 individuals had itching, burning sensations, or redness of the skin due to contact dermatitis. All the unwanted effects disappeared spontaneously after stopping the treatment. There were no long-lasting consequences of Mederma treatment.
Persons allergic to onion or other components of Mederma cannot use this product. If you suffer from some chronic skin condition, contact your doctor before using Mederma.
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