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I would like to know something about ALS. My wife is suffering from it and as I understood her muscle tonus will deteriorate, making her more and more dependent on other people's help. For now she feels good, minor symptoms are present, but not that dangerous. She has an excellent mind, poor motor function with ALS are not killing her spirit and intelligence. Will it be like this until the end?

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ALS is a tricky disease. People can become very dependent on someone else's help regarding basic motor functions, but still maintain healthy mind. Of course, you realize that this can make ALS patients very desperate, nervous, knowing the fact that cure is not waiting behind the corner. That is why their closest ones must be present for help, all the time, all the way.
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