I've heard that taking Diphenhydramine (Benadryl) on a regular basis can relax erectile tissue and lead to erectile dysfunction. Has anyone else heard of or experianced this?
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Yes of course, this type of "medicine" is very bad for people. Heres a link that may help you out: en.wikipedia.org/wiki/Diphenhydramine#Side_effects
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It is had just the opposite effect with me. I take one pill in the evening to help me sleep and I have experienced an "Awakening" in my penis, not fully erect but better than before I started taking it.
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