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Can the BK Virus prove deadly in an 8 year old patient with NK Cell Leukemia?

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The BK polyomavirus proves deadly in an 8 year old patient with NK cell Leukemia. The BK virus has been known to not have severe consequences of infection, except for in the immunosuppressed, of which a Leukemia patient may be.

Leukemia is a term that refers to cancer of the white, infection fighting, blood cells. When an 8 year old has Leukemia, a large number of white blood cells develop in the bone marrow, crowd the bone marrow, and flood the blood stream. Because the white blood cells, normally, help to fight infection you would think a large number of white blood cells would be a good thing. However, it is not.

With such a large number of over crowded white blood cells, the white blood cells cannot perform their proper roll of protecting the body of infection. With this defense mechanism let down, viruses, such as the BK virus can manifest itself and ultimately attack the kidney, cause a hemorrhagic cyst, or even cause cancer in the bladder.

REFERENCE(S):

1.Wikipedia, 2008. BK Virus. Wikimedia Foundation, http://www.en.wikipedia.org/wiki/BK_virus

2.Robin E. Miller, M.D., 2007. Childhood Cancer: Leukemia. KidsHealth and the Nemours Foundation, http://kidshealth.org/parent/medical/cancer/cancer_leukemia.html
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basically low level and uninformed. Fails to shed a clear light on possible problems relating to the perhaps dormant presence of the virus and the consequences of therapy. Problems may well be related more to the reduction in mononuclear leucocytes than the more commonly reported reduction in granulocytes - being the common cause of susceptibility to infection.

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