I have 45 years and my PSA is elevated. PSA was 1.4 in 2003.and then rose to 2.6 in 2004. Now it’s 4.0 and total PSA was 5 percent. I have done ultrasound and needle biopsies and both were negative. How serious that can be? Could it be some other reason for fluctuating PSA then prostate cancer?
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There are so many parameters to help determine is patient should have prostate biopsy. Important is fact if you have history in your family of prostate cancer. Your PSA (prostate specific antigen), seems to be on the high side. Velocity or rise in your PSA related to time sure is cause for concern. Sure is that you need another biopsy because of your free PSA range. Studies had shown that 20 or 25 percent of patients with PSA between 4 and 10 ng/ml will have cancer. Because you are young considered by a urological measure I think there should be performed another biopsy. If your follow up biopsy is negative you should continue your PSA closely. If there is not significant rise then third biopsy may not be indicated. Maybe you have falsely elevated PSA, especially if you have had infections of prostate. Elevated PSA doesn’t mean you have cancer but merely suggests that you are at increased risk.
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