About a year ago, aged 66, I was diagnosed with PD after brain scans. I had previously assumed that my increasing LH weakness was linked to mild childhood polio damage on that side, so was probably a bit later in being diagnosed than I would otherwise have been. My question relates to depression and antidepressants. I have been treated for depression, since being eventually diagnosed aged 17, with various medications and counselling over long periods up to the present. I've read that the tricylic family of drugs may adversely react with Madopar, the medication currently prescribed for me. I took tricyclics for many years, until I developed supra ventricular tachycardia, a recognised side effect. I was immediately taken off those drugs, must not take them again, and am being currently treated with Citalopram. I suppose I am wondering whether my long term use of antidepressants to help with a pre-existing depressive condition has contributed to my developing PD. Also, if a child suffers from depression during development of the brain, which seems to then maintain a long-term predisposition to the illness, would that also indicate a pre-disposition to PD? And, thirdly, asking for a crystal ball opinion, what will happen in my future? The Madopar has a 'raising' effect on my mood which, for me, is quite enjoyable! So, I suppose I should consider lowering my Citalopram dosage. But I am v aware of maintaining my mental balance - I really don't want to slip back into my painful thoughts - so am nervous of any change to the situation including that which may come with the progress on the PD. Has anyone any thoughts to contribute. As a relative newcomer to this situation, any advice will be v welcome - especially as I have no family for support. Jacey
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