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Hi, my mother has been diagnosed with pulmonary tuberculosis. I am very concerned about the outcome of this infection, because the doctor has talked to me about the complications that may occur. He said that the tuberculosis can develop into a chronic condition. Can you tell me why is tuberculosis so hard to cure?

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Hi, tuberculosis is a serious condition because the bacteria that causes it is highly contagious and very resistant to antibiotic therapy. The infection might last up to two years and even then the patient is not cured because some of the bacteria stay trapped inside the granulomas surrounded by the scar tissue. These bacteria can be reactivated after several years and cause even more damage. The chronic state of tuberculosis is conditioned with the antibiotic resistance of the bacteria. Because of this resistance, treatment considers the use of the combination of three antibiotic drugs for two months and the combination of two drugs for the rest of the treatment. I am very sorry to say that in cases like your mother's the prognosis is not very bright. The longer the infection lasts the poorer the outcome is.
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Hi,

Tuberculosis is caused by a bacteria which multiplies slowly which means that it is hard to kill and medication needs to be taken over a prolonged period. The key from getting better (and YES LOTS OF PEOPLE GET 100% BETTER) is taking the medication exactly as the doctor tells you. Also make sure that your mother gets a very healthly diet with lots of fresh fruits and vegetables as well as vitamin supplements to promote her immune system. lots of rest, moderate exercise, low stress levels, lots of fresh air and sunlight as well as personal hygiene are imperative in curing the disease. Remember over 98% of people with active TB that seek treatment are cured. Keep in mind that TB affects people that have immunocompromised bodies (hence its high prevalence in HIV positive people). Assuming your mom is not HIV positive the way to get her better is to build her immune system so that it can help the medication defeat the bacteria. Know that 90% of people that come into contact with TB bacteria do not develop active pulmonary TB because their bodies immune response is strong enough to keep active TB at bay.

TB becomes chronic primarily due to not following the medication regime properly. many people start to feel better before 6 months is up and stop taking the meds...beacuse the bacteria multiplies slowly some will still be in the body. Also people forget to take their meds everyday, as 6 months is a long time.

Don't worry too much, just make sure your mom gets healthy lifestlye and takes her meds. I pray it will not become a chronic problem.

As for antibiotic resistence, some strains of TB are resistant to drugs which is why your mother will be treated with a combination of drugs, as long as she takes her meds properly she will not promote her tb to become resistant. Note that the majority of the tb strains present are not multi drug resistant which means that it is susceptable to at least one of the drugs available now a days. In Africa some strains of TB exist that are multi drug resistant, these predominantly affect HIV positive people and even so there is second line treatment available.
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what will happen to the patient if will become chronic ptv?
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what will happen if it will become a chronic problem?
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