I am on the depo but just got My first shot in feb. I was on antibiotics and i know it doesnt Cancel the shot but it can make it less effective. I had unprotected sex twice while on those. I didnt think I was pregnant but My abdomen Is tender, I have the pain in joints, and some náusea. All those just started within the past two days. I had sex just last weekend. N today I was running and I went to go to the bathroom and there was a little bit of the Brown discharge u get before a period but im not suppose to have My period until the last week in April or the first week in may..and If i am pregnant Did running do anything? I also have back aches n tiredness.