Delayed Pressure Urticaria

Hello everyone,

I've been reading your posts off and on for the last 6 months or so, and I believe I have found a solution to my Delayed Pressure Urticaria.  I've had to deal with the wheals or hives for over eight years now and have been getting worse in the last few.  After finally mentioning this to the doctor 2 years ago, she mentioned researching urticaria.  Side note-- strangely, my wife developed Solar Urticaria about 2-3 years after me. 

So I ran across this book about 4 months ago called Wheat Belly.  It mentioned various dermitituses and urticaria, among other things caused by the new wheat species commonly used in the last 30 years. 

So I tried the wheat free diet for 2 days and lapsed.  Then I made it for almost 5 days lapsed.  Next I went wheat free (not just gluten) for a whole week.  No change in urticaria. 

About 5 weeks ago, I was able to stay wheat-free for 2 weeks.  About two and a half weeks in, I spent about 4 hours on and off my knees setting tile.  Normally, I would not be able to walk the next day without prednisone and pain killers due to the delayed-pressure urticaria.  Aside from some minor soreness in legs and back, no urticaria.  No burning.  No itching.  No disabling swelling. 

That weekend I installed a ceiling fan.  Normally after being up and down a ladder in sneakers would have urticaria swelling my arches and toes (like you are walking on great masher marbles) to the extent that I couldn't walk without being in severe pain.

Now my neighbors offered me pizza last week for lunch while I was doing some work for them.  Two small slices put me back into urticaria for over five days. 

I had Domino's gluten-free pizza July 3rd, hoping the urticaria was only gluten induced.  No such luck.  I set some tile last night and required prednisone before I went to bed. 

So 2-3 weeks wheat free seems to be working for me.   I hope this helps.  I still can't believe this worked.  I've been at my whit's end with this. 

Good Side note--Beer doesn't seem to be causing the urticaria! 

unfortunately i totally understand. good luck. i'm going to try the guaifiesen/salicylate method next. i've had this over 20 years.

Hi, I have also had this for a long time. I was on a steroid which ceased the symptoms, but has terrible long term effects. I have recently stopped and am now in pain, but trying to treat is homeopathically. I am having some initial success with Arnica. I would love to be in touch with other people who have it, and maybe figure out what we all have in common, i.e. why we have it, and therefore perhaps how we can treat/prevent it. My email is _[removed]_. Please email me, if you want to share info. Thanks!

I use Zyrtec which seems to help. That's the only thing my doctor recommended.

2 days ago, i noticed red spots on my feet with a white outer circle, i thought it was nothing so i left it. But today, i woke up with these spots all over my body, all over my back, my feet, my stomach, everywhere! I went to my doctor and he thought it was an allergic reaction, but I'm not too sure. It is extremely itchy and when i am picking something up or walking for a long amount of time, it can hurt an start to itch a lot. What would you suggest it is? By the way I'm only 13 years old and i am healthy (no daily medication or family history of problems)

i have the same disease and use "Neorine" antihistamine tablets i tried a lot of other tablets but only they work and i can have a normal life again with 1 tablet every morning. wish it would help you also! regardss gerda endemann

I can't seem to find anything on "Neorine" online. What is it please? And where do u get it? Thank you, Lynn

is the wheat free still sorking for you?

is the wheat free still working for you? thanks, lynn

it is a long acting ,non sedating,anti allergic
5mg Desloratadine
i buy it in saudi arabia and it is made there by SPIMACO

thank you. i was hoping maybe it was something i haven't tried. but i have--just a different name. hope you are doing well. this is a strange and bizarre condition we have. take care, lynn

Hello all,

Cetirizine effectiveness testimony

I'm a 40+ female. I'm tall and relatively thin, and according to my Dr., otherwise in perfect health.  I'm not sure how long I've had DPU, but this time around, I've been dealing with it for about 5 years. The severity of my affliction seems mild to moderate.  I.E., I don't have to sleep on my back, but leaning against something, sharp 'slaps' and carrying anything with a wire (or similarly thin) handle is a definate NO-NO. I can't wear heels more than 6 hours, and thin belts, halter straps, etc. are not allowed in my wardrobe. Finally, I have to carry a seat cushion in my car for ball parks or patio events where cushioned seats are not available.  Nothing new there, so let me fill you in on my treatment.

First, let me say that I have NOT found a cure.  But I have some compelling evidence that 1 24-hour dose of Cetirizine (Zirtec-generic) daily is quite effective in REDUCING the severity of reaction to the point that the above is the extent of my limitations.  I started taking it regularly about a year ago.  It wasn't for a couple months that I noticed improvement, but not long after that, I found myself more free and less obsessive about direct physical contact in general.  Well, a couple weeks ago, I ran out, and thought I would do a test-run to see if my condition was actually improving, or if the Zirtec was indeed helping (and to what degree). It wasn't even 3 days later that I fould the answer, and it wasn't pretty.  Essentially, I was miserable, had contact wheals whose source I couldn't recall, and several that I could. Some of them even bruised up. Throw in the accompanying fever and 'flu'like symptoms, and viola, I had to take a day off work (luckily it was a Friday).  I resumed my Zirtec Saturday morning, and am hoping for a quick resumption of benifet.

Potential wheal treatment:

My Dr. prescribed me some Lidocaine for lazer treatments I had. One day, I had a few wheals on my fore-arms and the itching was so bad, I nearly scratched myself raw before I realized it. I used a Q-tip and applied a medium coat of Lidocaine to the affected areas. The relief was nearly instant. After it 'soaked in' for about 5 minutes, I then washed it off with cool water (so I didn't get it on everything). I can't tell you how great it felt to be relieved of the itch!!! My next step is to find out if Lidocaine has any long-term use impacts, and if not, will be asking my Dr. to prescribe plenty more.

Additional background:

As a pre-teen, I remember having what appeared to be a severe case of hives that lasted about 3 days - fever, itching, the works. Nothing persistent or long-term beyond that, though.  Since then, I would occasionally have a wheal here and there (usually un-explainable).  It wasn't until about 6 years ago that things started getting out of control. My GP initially told me it was most likely just hyper-dermographism, which was good enough for me then.  But after a few more months, I started connecting the dots and drawing relationships between the wheals and the contact events that caused them.  After expressing the noted (and quite puzzling to me then) delay, she suggested I research DPU.  Sure enough, when I read the testimonials, I affirmed that the symptoms fit my issues to a PERFECT T!! I was overcome with elation to finaly have an explanation for the issue, and admittedly thankful that it wasn't as severe as some testimonials I read in my research. Anyway; for the next 18 months, my symptoms steadily got worse, until I started my regimine of Cetirizine. Now, per my above testimonial, the "untreated" severity appears to be approaching the moderate-severe range. Lets hope they keep it on the shelf!!!

I am so f****** depressed and fed up with having this affliction. I don't know what to do any more. It doesn't even sound like I have one of the worse cases...at all....

I can't find an appropriate job that doesn't just kill my hands or feet, so, I've had to move back to my family home (I'm 27) as I can't afford my rent...

I've lost all my friends because I can't go out whilst wearing crappy (yet so comfy) sweat pants/jogging bottoms or do ANYthing and getting there using any public transport sends me off (standing on buses/tube)...

No one in my family understands it and just thinks that I'm lazy and that I should just 'get over it and carry on'...my father gets pissed off at me and forces me to go over and over to the Dr's, when, each time I go, it's ME that has to explain to the Doctor what DPU is and they're usually just mildly interested in something that they haven't heard of (although, the last one that I went to, refreshingly said: "Well, it's so rare, there'll never be any clinical trials or drugs created for it as the Pharmaceutical companies won't make enough money from it" !!! I would have given him a high 5 if my hand wouldn't have probably swollen up afterwards... ;D  )

I've had this for 8 years now...i just don't know what to do - I'm so sad all the time (I have depression (only mild) as well, and by god does this make it a whole bloody lot worse)

I'm just so lost. This has ruined my life. Or rather, helped ruin it......I dunno. My thumbs have gotten so swollen on a number of occassions that they've bubbled up and split - luckily it's only my thumbs that have done that - they are now permanently sensitive to heat.

I'm just pretty low at the moment I suppose so am looking for some words of reassurance from people that understand! Sorry to put such a bloody dampner on this thread!

I hope you're all doing okay.

Thanks,

D

Hi D
I'm so sorry for all you're going through. 24 years ago when I first got this I ended up on disability for a couple of years. Not sure if they gave it to me based on DPU and CIU or how depressed I was. It went away for years and then came back a couple of years ago. I completely understand about family and friends. When I had cancer everyone understood. Didn't need chemo so as far as I'm concerned cancer was nothing compared to this. I saw a psychologist today just to talk with someone who has to listen! Take care. What are u taking or doing for it?

I'm on this on my phone so I'm not sure if I'm replying right...but this is the best thread I've found so far and I want to keep it accessible! Similar story to everyone else...24, had it for almost a year now... Kept being told I was allergic to something, so I replaced my bedding, soaps, laundry detergent, medications, diet, even my mattress (read that memory foam can cause allergies)...none of that worked of course... The day I stumbled across a DPU site I felt like crying, I was so relieved to find out what this was. Doc prescribed a whole bunch of meds, including stronger and more damaging stuff for my ulcer, to counterbalance the prednisone etc.

First, I recommend to ALL of you to watch "fat, sick, and nearly dead".. He has a similar or the same condition, and puts it Into remission by changing his diet and juicing fruits and veggies...it's amazing. Not only that, but I decided to try this out (you all know I'm sure how anything is worth trying to get rid of this c**p lol)...I juiced for only five days, and surprise- no hives the whole time! It was amazing. As soon as I ate c**p food again and had a dr pepper, I had an awful outbreak. So, I'm gunna try a clean diet- no junk, very little sugar, lots of veggies and fruits. I would DEFINITELY reccomend a diet change to everyone...

Other than that, I'd love to keep in contac with anyone who'd like some mutual support.. I'm dealing with a whole bunch of friends and family that just don't get it...either they think I'm being dramatic or they don't understand that it hurts too much to walk :/ so _[removed]_ if anyone wants to chat! Good luck...