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what is difference between loratadine and fexofenadine?

i'm asking this because, my husband was on allegra d 24 hour and is now on claritin d 24 hour. he says he can not take claritin, due to the fact that it is not as effective for him as allegra.


Fexofenadine (Allegra) is drastically more effective at suppressing histamine flares than loratadine (Claritin). Speaking from personal experience, Allegra works much better than Claritin. However, if you have the option, cetirizine (Zyrtec) is more effective than both. And, if you can find Zyrtec-D, there's an added dose of pseudoephedrine (Sudafed) which clears up your sinuses immensely and is better than taking OTC nasal decongestants like oxymetazoline (Afrin) or phenylephrine (Sudafed PE).