Isotretinoin, commonly known by brand names like Accutane, is one of the most powerful oral medications used to treat severe and resistant forms of acne. It is especially effective for nodular, cystic, and inflammatory acne that does not respond well to topical treatments or antibiotics.

While isotretinoin is highly effective for moderate to severe acne, it is not usually prescribed for mild or comedonal acne (blackheads and whiteheads) unless other treatments have failed. In those cases, topical retinoids or benzoyl peroxide are generally preferred as first-line options.

Isotretinoin 20mg works by shrinking oil glands, reducing sebum production, inhibiting acne-causing bacteria, and preventing clogged pores—making it effective against multiple acne triggers. It often leads to long-term or permanent remission, even in the most stubborn cases.

However, its intensive side effect profile—including dry skin, potential birth defects, and mood changes—means it's not suitable for everyone or all acne types. A dermatologist will determine whether it is appropriate based on acne severity, past treatments, and patient health.

In summary, isotretinoin is extremely effective, but mainly reserved for moderate to severe acne, not all types.

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