Market positioned Biotin as a potential aid for patients suffering from hair loss, nail brittleness, skin blemishes, and lists many other benefits. So far, in our reviews of the product, we determined that biotin for hair growth can be an effective hair loss treatment only if you have a deficiency in your biotin levels. If you have average values of biotin, there was no difference to regaining your hairline. If you are pondering "can biotin strengthen my brittle nails?", we have also discovered that there are limited benefits from this agent, as well. Systemic diseases or brittle nails due to side effects of medications are two of the main reasons why biotin will not make any difference in your nails. In this investigation, our focus is on biotin benefits for your skin. We will try to answer does biotin help treat acne?
Skin Conditions Due to Biotin Deficiencies
Biotin deficiencies are a rare occurrence, but with specific diets, we inadvertently predispose ourselves to low levels of biotin without even knowing it. If your diet full of egg whites, that may be a good way to lower your cholesterol panels, but unfortunately, this diet also has been linked to lower levels of biotin in your eating habits. In one investigation run to determine if consuming 1 egg white a day for 1 month made a significant impact on biotin levels, it was determined that even eating such small portions of eggs could start to deplete your body of natural biotin levels.  Don't worry though, there are several other foods rich in biotin that you can eat to replace your missing levels.
If the biotin deficiency becomes severe, you will start to notice systematic changes throughout your body. Your body will signal you have low levels of biotin because biotin is too crucial for physiological reactions in our body to be ignored. Some of the most prominent changes are hair loss, brittle nails, and skin rashes at first and then more severe changes, and some of them are neural impairment if levels of biotin are still low .
When focusing on skin manifestations of biotin deficiency, the most common skin blemishes will be alopecia and a scaly, red (erythematous) rash localized around our mouth and anal canal . As the rash progresses, it is entirely possible that you can start to notice opportunistic Candida infections that can take advantage of our weakened skin. Candida is a fungus that naturally grows on our skin but does not cause any issues because our skin is a strong barrier to protect ourselves from infections. When there are cuts or rashes on the surface of the skin, this harmless fungus can become more problematic and start causing infections like ulcers, pimples or abscesses. 
Will Biotin Help Treat Skin Blemishes?
When it comes to determining if there are any biotin benefits for your skin, we can begin to look at treatments for people with severe biotin deficiencies. Several medication studies determined that when patients suffered from congenital biotin deficiencies, it was essential that patients were treated with biotin and corticosteroids to stop rashes from becoming life-threatening. Concluding from these studies, it is obvious that patients who have a biotin deficiency will benefit from biotin supplementation.
Due to the severe systemic involvement of biotin deficiencies, biotin supplementation will not be enough to try to treat skin changes that you can notice on its own. In this case, a conventional medication that doctors often prescribe goes by the name of isotretinoin. You may know this medicine already in its more familiar form Accutane. Accutane is an active agent at treating your skin blemishes — it will resolve problems with your acne in over 90 percent of the time .
Accutane is a great help to alleviate problems you may have with your skin, but studies also indicate that Accutane can have a dramatic effect on the level of biotin. In one study conducted on 42 patients suffering from severe cystic acne, researchers determined that this therapy causes a significant reduction in the level of biotinidase, which is a protein that helps release biotin in the body. When levels of the protein levels are low, it is only natural for biotin levels to also lower. As a result, you will need to use biotin supplementation in addition to Accutane therapy in order to help benefit your skin. 
All in all, we now have a better answer to our question of "does biotin help treat acne?" When you are suffering from a severe skin manifestation of biotin deficiency, you will need to take supplements to realize the biotin benefits for your skin. Much like our study looking at biotin for hair growth or as an effective hair loss treatment, it would seem that the only benefits that you can notice from biotin are when you already have a biotin deficiency.