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I am doing some research on this because my husbands mother has this disease and his grandmother is deseased from it. My husband and I are concerend that he could pass it down to our children. His mother told me that it is more common in female, but what I have seen so far shows me that, that is not the case. We have 2 young boys ages 4 and 5. Is it possible that they could be carring the gene? We would like to have more children and are afraid that if we have a girl she will inherit it. My husband has not been tested. Is this something that we should do?

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What you found out seems to be right – there is no proof that girls tend to inherit spinocerebellar degeneration any more than boys. From what I’ve read, any child of an parent with the disease has a 50 percent chance of inheriting the disease gene. If the child inherits the disease-causing gene, he or she will eventually develop symptoms of the disease. A child who doesn’t inherit the disease-causing gene will not develop the disease and doesn’t pass it on to the next generation. So, from what I understand, if your husband hasn’t got it neither do your sons o any of your future kids. No matter how scary, it’s probably better to know. You should find out if it’s possible to test for this genetic disorder as part of pregnancy planning.
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In my family ( on my dad's side) most of the males have noticeable symptoms that have been inherited for generations. we all vary in how early it was noticeable and which symptoms we have and to what degree. the women, for the most part, show little or no symptoms. they do carry the gene as the majority of their male offspring do have varying degrees of this condition. i was 1 of the first diagnosed with "spinocerebellar degeneration" at about age 10 because there were things i couldnt do well in P.E. i am now 52 and it is pretty obvious by the way i walk or jerk for no apparent reason. i am in pain most of the time but not to the point of medicating. i have a wheelchair that i rarely use but admit that sometimes i wish i had it with me instead of leaving it at home. so having this condition all my life,i'm somewhere in the middle as far as far as how much of an impact its had on my life compared to the men in my family and from what ive read. its just now really becoming an issue. growing up and living my life wasnt much different and not that big of a deal living with. i have 2 daughters. 4 grandsons and 1 granddaughter. the oldest at 13 is into karate and although does have the same kind of walk as i do, so far hes had no problems and is a normal 13 yr old boy who is actually above average in sports. i really hope this was some help at least. good luck and i wish you the best in whatever you decide.

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