Hi,I'm cleo,glad to say I was very skeptical!!!!I read up on duromine and began to fear some of the advise that was posted,but I had the courage to go get my prescription,day 1+2 sleep deprived,but had no appertite whatsoever,I weighed 97,5kg before taking them,by the end of week 1 I was 89.3Kg I was so shocked!I tried on some tops that couldn't fit me,and wow was I surprised!all the buttons closed!!!!I'm now on the 3rd day of week2 I will weigh in at the end of the week,and there is this jacket I want to wear this weekend I have not closed the buttons for 2years,can't wait! My advise is yes!plenty of water and fruits,small excersise(I do tummy crunch + 10 sets of stair climbing a day)Goodluck