I am interested to know how much genes counts following regions: sDp2, unc-93 to dpy-19, unc-22 and eTI-balanced region? I am very interested in to know percentage of the genes that can be mutated to a lethal phenotype.
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I gave give you calculation of Barnes et al. from1995. The sDp2 balanced region of chromosome I has a minimum of 225 essential genes which is approximately 22% of all the genes in the region, unc-93 to dpy-19 region of chromosome III has a minimum of 293 essential genes which is approximately 24% of the genes identified in the genomic sequence, unc-22 region of chromosome IV has a minimum of 55 genes (Clark et al. 1988), which is 10% of the total genes, eT1-balanced region of chromosome V has a minimum of 120 essential genes ( Johnsen and Baillie 1991), again about 10% of the total.
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