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I took a tiny piece of my subutex like 6 hours ago, it was like a half of a quarter. I have a killer migraine so i was wondering if it would be safe to take a couple Ultrams right now?

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First, it is never advisable to take a pain medication with Subutex (buprenorphine) unless prescribed by your doctor. These are prescription meds given to you by your doctor, correct?

Second, from experience I can tell you that Ultram (tramadol) does nothing for migranes.

So my advice is no, don't take a couple or even one Ultram after taking Subutex.
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