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Coenzyme Q10 (CoQ10) is a vitamin-like substance that is normally produced by the body and is essential for functioning of several cells and tissues. The levels of CoQ10 are noted to decrease as age progresses.
Levels of this coenzyme are low in individuals suffering from disorders such as Parkinson’s disease, heart disorders, diabetes, cancer and HIV/AIDS. Supplementation of CoQ10 has been believed to benefit individuals suffering from such disorders and is also reported to be helpful in the prevention of these disorders. Apart from its antioxidant function, several studies have reported about the benefits of CoQ10 on the immune system.1

Boosting the Immune Function

Studies have reported the beneficial effects of coenzyme Q10 supplementation in the prevention of infections and cancers. Many disorders including infections and cancers are mainly related with the abnormal functioning of the immune system. Proper regulation of the immune system is required for the initiation of immune response and the control abnormal responses. Numerous substances including CoQ10 have a role in the regulation of the immune system and adequate levels of these substances are highly necessary.1, 2

Administration of CoQ10 with or without vitamin B6 was noted to increase the blood levels of different types of T-lymphocytes. These lymphocytes are required for killing harmful microorganisms and clearing the toxic substances. Other effects were reported on the phagocytic rate, levels of antibodies in the blood, and reduction in the number of infection.3, 4

Individuals suffering from immune system disorders such as AIDS are noted to suffer from deficiency or abnormal functioning of the different types of T-lymphocytes and its associated cells and proteins. Supplementation of CoQ10 in normal subjects was noted to increase the ratio of different T-cells which can have a beneficial role in individuals suffering from immune system related deficiencies. Further studies are in progress to demonstrate the efficacy of CoQ10 in slowing the progression of immune disorders. Another study conducted at the University of Texas noted that individuals suffering from allergies had very low levels of CoQ10 substantiating its role in the immune system. Supplementation of CoQ10 along with other medications in such individuals can improve the immune response and result in a decrease of allergic symptoms.4, 5

  • 1. Gazdík F, Piják MR, Borová A, Gazdíková K. Biological properties of coenzyme Q10 and its effects on immunity. Cas Lek Cesk. 2003, 142(7):390-3
  • 2. Folkers K, Morita M, McRee J Jr. The activities of coenzyme Q10 and vitamin B6 for immune responses. Biochem Biophys Res Commun. 1993 May 28, 193(1):88-92
  • 3. Folkers K, Wolaniuk A. Research on coenzyme Q10 in clinical medicine and in immunomodulation. Drugs Exp Clin Res. 1985, 11(8):539-45
  • 4. Folkers K, Hanioka T, Xia LJ, McRee JT Jr, Langsjoen P. Coenzyme Q10 increases T4/T8 ratios of lymphocytes in ordinary subjects and relevance to patients having the AIDS related complex. Biochem Biophys Res Commun. 1991 Apr 30, 176(2):786-91
  • 5. Ye CQ, Folkers K, Tamagawa H, Pfeiffer C. A modified determination of coenzyme Q10 in human blood and CoQ10 blood levels in diverse patients with allergies. Biofactors. 1988 Dec, 1(4):303-6.
  • Photo courtesy of Jason Tester Guerrilla Futures by Flickr :

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