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While I was watching some educational program on television I have heard something interesting. They said how neutrophils represent more then 50% of total circulating leukocytes. What especially interested me was fact that neutrophils constitute the first line of body’s defense. Since I always was impressed with perfection body’s immune system this was amazing to me. I want to know more about those little but so important cells in our organism.

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Neutrophils are also known as polymorphonuclear leukocytes. They represent first line of defense against infectious agents or non-self substances that penetrate the body’s physical barriers. Once inflammatory responses in irritated, nutrophils are the first cells will come to fight. They will be first cells recruited to sites of infection or injury. Their targets include bacteria, fungi, protozoa, viruses, virally infected cells and tumor cells. Their development in bone marrow takes about two weeks. Senescent neutrophils are thought undergo apoprosis or programmed cell death, prior to removal by macrophages. Variability is significantly shorter in individuals suffering from infectious or acute inflammatory diseases when the tissue requirement for newly recruited neutrophils increases considerably. Subpopulations of neutrophils have been identified with various criteria. These cells exist not only in dormant or resting or activated states. They are also in various intermediate stages.
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Is 44 too low?
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