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September 13th 2016 is World Sepsis Day. Why not take a look at one of the most common and deadly diseases, and find out why it's called the "silent killer".

Sepsis in Babies

If your babies and children under five have these symptoms, go straight to your nearest emergency medical care:

  • High-pitched cries of distress
  • Respiratory rate of more than 40-60 breaths per minute
  • Heart rate of more than 140-160 beats per minute
  • Rash or mottled skin
  • Temperature of less than 36.C or more than 38.C
  • Unresponsive - call an ambulance

Sepsis in Children

If you have a child aged 5 to 11, watch out for the following symptoms of sepsis:

  • Altered behavior
  • Complaining of feeling ill
  • Respiratory rate of more than 25-29 breaths per minute
  • Heart rate of more than 115 to 130 beats per minute

Aren't some of those sepsis symptoms...well, very general?

On the one hand, yes. Some of the symptoms that can point to sepsis might send you to the doctors for a check-up with every full-blown flu. But that's not necessarily a bad thing.

A recent study in The New England Journal of Medicine discovered that, under the old guidelines, known as SIRS, medical professionals missed up to one in eight severely septic patients. And, arguably, the SIRS guidelines were more even generalized than the new SEPSIS guidelines, advising medical professionals to watch for a fever of over 100.4F, a heartbeat above 90 per minute, and a respiratory rate above 20.

In addition to the symptoms that send us to the doctor (the new SEPSIS guidelines), our doctors are advised to look for (in older teens and adults):

  • an altered mental state (for that reason, always try to see a doctor who knows you)
  • a respiratory rate equal to or greater than 22
  • a systolic blood pressure equal to or less than 100 mmHg.

One of the main problems with sepsis is that it initially resembles the normal response to infection in otherwise healthy people. As Dr Maureen Baker, chair of the Royal College of GPs, says: "The diagnosis of sepsis is a huge worry for GPs as initial symptoms can be similar to common viral illnesses."

How is sepsis treated?

Sepsis requires a high dose of antibiotics, usually delivered in a sterile intensive care unit.

The treatment of sepsis has three aims:

  • Halt infection
  • Protect the organs, which are at risk of failing
  • Prevent a drop in blood pressure

Before the strain of bacteria that caused the sepsis can be identified, patients are treated with a broad-spectrum antibiotic (one that treats a wide variety of infections). When the infection is identified, a more specific antibiotic will usually be chosen, to target the infection.

Sometimes other treatment, such as kidney dialysis, may be required as a supportive treatment to keep the patient alive.

Long-term effects

Most people recover completely. However, some patients who were already weakened suffer long-term complications.

One common complication is permanent kidney damage in patients who already had some kidney impairment. This kidney damage may result in a need for lifelong dialysis.

What should I do if I think I have sepsis?

  • Make an urgent appointment or go straight to the accident and emergency department/emergency room if you have/have had an infection and you have any signs of sepsis.

  • Tell your doctor/healthcare provider, "I am concerned about Sepsis".

Also ask your doctor about sepsis if you have had surgery and you are feeling worse or are not feeling better a few days after surgery.

Remember, sepsis is a medical emergency.