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Muscle pain with slight elevated Cpk levels also elevated sed rate. Leg muscles burn and weak. Dr doesn't think my leg muscle pain has anything to do with my elevated Cpk and sed rate. She thinks the aches are from depression. I disagree.

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Health Hero
1626 posts

Hi, guest.

Depression is not a known cause of elevated CPK levels or muscle pain. CPK (creatine phosphokinase) is an enzyme found in muscles, and elevated levels of CPK can indicate muscle damage or injury. Muscle pain and weakness are also common symptoms of muscle injury or inflammation.

While depression can cause physical symptoms such as fatigue, headaches, and body aches, it is not typically associated with elevated CPK levels or muscle pain. It is possible that your muscle pain and elevated CPK levels are due to an underlying medical condition, such as a muscle disease or inflammation.

A high sed rate (erythrocyte sedimentation rate) can indicate the presence of inflammation in the body, but it is not specific to any particular condition. Your doctor may need to perform additional tests to determine the underlying cause of your symptoms.

It's important to have a conversation with your doctor about your concerns and to discuss other potential causes of your symptoms.

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