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Hi, folks. My brother complains he has an irregular heartbeat. He suspects he has arrhythmia. He was at the doctor’s several months ago and he was found nothing. I wonder whether irregular use of some drugs can cause arrhythmia. I would gladly hear out your opinion about this. Thanks in advance.

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Hello. Of course that irregular use of many drugs can cause arrhythmias. Metaraminol is alpha adrenergic agonist which stimulates releasing of norepinephrine. It was used as a vasoconstrictor in treating hypotension. Antidepressant, nortriptyline and other tricyclic antidepressants can also cause arrhythmia. Drug overdose is also something that leads to arrhythmia. Bretylium block a release of adrenergic transmitters and it can also cause arrhythmias. And the list goes on. I hope your brother will be all right. Bye!
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