Male, age 62, good health, exercise regularly, annual physical just done, 6'2" 190 lbs. Taking Simvastatin, Nexium and Zyrtec nightly

This may be totally unrelated to Nexium as it seems each time this happens I have had a large evening meal (for me) accompanied by wine and beer and moderate drinking till 9:00 PM. I do not feel bad or intoxicated when I go to bed at roughly 10:30PM but I usualy awake at 3:00 AM or so with stomach flutters and in a full body sweat. I feel like I have the flu. It normaly subsides by noon the next day and is also accompianed by soft stool.

This occurs about three or four times a year and it usually occurs, but I cannot say for certain always occurs, when I forget to take Nexium at bed time. Is this due to the lack of Nexium, the presence of larger than normal amounts of food, an increased intake of alcohol or some other thing? Any ideas?