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What type of mental side effects has anyone seen with Systemic Lupus Erythematosus ? A good friend is the object of abuse of a strange way because her husband has SLE ? or could it be something else ? Paranoia , anger , accusing , degrading , physical violence , are evident ! Maybe he's just a sick person period and the SLE dosen't have much to do with it ? Looking for help ! Stephen

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Involvement of the brain can cause personality changes, thought disorders (psychosis), seizures, and even coma. Damage to nerves can cause numbness, tingling, and weakness of the involved body parts or extremities. Brain involvement is called cerebritis.
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