Methenolone (Primobolan®) is generally advised in case of men suffering from the deficiency of a hormone known as androgen in men. In some rare instances this drug has also been advised to treat a condition known as aplastic anaemia which is mainly characterised by the deficiency of blood cells.
In some other instances it has been advised to counter the abnormal weight loss associated with certain disorders or following major trauma. It is illegal to obtain and use Primobolan® without being prescribed by the doctor. Primobolan® is not approved for use in the United States.
Effects on the body
Primobolan® has been advised for women suffering with breast cancer in some instances as it has been believed to aid in the reduction of the tumour size. The anabolic steroids such as Primobolan® reduce the excretion of nitrogen from the tissue.
This retention of nitrogen within the muscle tissues aids in the building of muscle mass to a certain extent. The muscle building effect may be present to a certain extent while no clear evidence about enhancement in athletic performance has been observed with the use of Primobolan®.
Primobolan® supposedly burns fat thereby reducing its amount in the body. This effect of Primobolan® has increased its popularity among athletes who look at building a lean mass with less fat in their body. Further it has been stated that Primobolan® prevents wasting of muscles and reverses the effects of anaemia. Anabolic steroids may enhance the formation of blood cells in some instances. In case of individuals suffering from chronic immune disorders such as AIDS, Primobolan® has been advised as immune booster drug.
Being described as Arnold Schwarzenegger’s favourite steroid, Primobolan® is widely abused in sports and bodybuilding. It is considered that it Primobolan® builds strength with adding bulk to the muscles. Primobolan® is generally more favoured by athletes as it helps them to maintain a lean body mass while improving the ability of the muscles to contract. Also it has been proposed that it is not associated with the common side-effects of other steroids such as acne, water retention, infertility and others. In case of body builders, it is used during the bulking or cutting cycles.
Chronic abuse of Primobolan® is associated with a number of adverse effects. Providing a constant supply of synthetic steroids to the body can have a multitude of side-effects on the normal functioning of various organs in the body. The body regularly requires steroids at a controlled level and is generally produced within our body. Loading up the body with steroids though may provide benefit to a certain extent; the harmful effects always have an upper hand. Some of the major effects have been discussed below.
Effect on heart
Prolonged use of Primobolan® has been associated with a wide number of effects both directly and indirectly on the heart. An increase in the blood pressure is commonly noted. Other effects such as abnormal changes in the cells and tissues of the heart and premature onset of heart related disorders are also noted in chronic abusers of anabolic steroids.
Effect on the nervous system
Occurrence of stroke has been reported in anabolic steroid abusers. Other neurological symptoms such as mania, hallucinations, mood swings and depression have also been associated with the abuse of Primobolan®.
Effect on the stomach and intestine
Ingestion of high doses of Primobolan® within short interval periods can result in vomiting and gastric irritation.
Effect on the liver
Primobolan® can alter the normal functioning of the liver resulting in the elevation of certain enzyme levels that can often be harmful. At times, it results in the increased incidence of jaundice in chronic abusers. Excessive use of anabolic steroids such as Primobolan® can result in a condition called peliosis hepatis.
This abnormal condition of the liver is generally characterised by the formation of cysts (fluid filled cavities) in the liver. These cysts affect the liver function and at times result in liver failure which may lead to life threatening situations. The incidence of liver tumours is also noted to be increased in individuals who abuse Primobolan®.
Effect on urinary system
Increased occurrence of cancer of the prostate gland has been noticed in anabolic steroid abusers. Prolonged use of Primobolan® is associated with increased proliferation of the cells and tissues of the prostate gland, a condition commonly referred to as prostate hypertrophy.
Effect on reproductive system
Various effects such as decrease in the functioning of the testicles, reduction in the number of sperms, impotence, and decrease in the volume of semen have been noted in men who abuse anabolic steroids such as Primobolan®. Loss of libido has been reported both in men and women who consume Primobolan® in high doses.
Women consuming high doses of Primobolan® tend to develop signs of maleness such as increased body and facial hair, hoarseness of voice and male pattern baldness. On the other hand, men may develop female features such as enlargement of the breast tissues.
In case of children, the use of anabolic steroids during early ages has been associated with cessation of growth of the bones. This affects the height and children or young adults consuming Primobolan® in high doses can have stunted growth. It has also been proposed that the sexual development in such children is also decreased to a certain extent.
Thus, Primobolan® has a lot of harmful effect when abused for body building. It should be avoided except under a few rare conditions when it is prescribed by the physician.