I had taken duromine about a year ago and started off on 15 and it done nothing so my doctor increased it to 40 I then started to loose some weight. I came off if it once I had lost the weight, well a year later I managed to gain 30kg so my doctor started me back on the 40ml, I am on My fourth day now and I'm having terrible side effects.. Only about 10 hours sleep within the 4 days, I have had diarrhea, the constant feeling I need to vomit, so tired yet my brain and body will just not switch off, when I need the energy during the day I just feel tired, extremely dry mouth, headaches and mood swings. I've read that these symptoms are meant to be rare and I happen to have a few of them which is making me think do I just stop or wait it out another week and see if the symptoms start to go.. These tablets cost me $139 like most of you would no there not cheap so If I decided to go back down to 15 there's going to be another $100. I have also read a lot of people saying just to excerise and eat healthy it's a lot harder than it seems, I had been skinny my whole life my heaviest weighing at 54 kilos I know weigh 92, and now matter what I do nothing seems to work. Very frustrating, hoping duromine will work for me again.. If anyone has has these same symptoms on the 40ml please let me know how you went and how long did it last for? Thanks.