A quick update- I have done the 23andme DNA test and it reveals I am a carrier of R117H (one copy).
This test doesn't cover all CF mutations so considering further testing.
This test doesn't cover all CF mutations so considering further testing.
Loading...
I also found out through 23andme that I am a CF carrier, having the common variant, got it from my dad's side. He had COPD, the chronic bronchitis variety. His half-sister on his dad's side had emphysema and lung cancer which she died of. They were heavy smokers, but I'm a non-smoker getting hard with respiratory infections. It took me 3 months to get over my last respiratory infection because my meds didn't work and it morphed into bronchitis. I was also diagnosed with GERD a year ago. There's familial diffuse gastric cancer running on my mom's side, so if I develop GI issues, I'm worried it will be far worse. When I'm well, the only thing I have to deal with is this wheezing "smoker's cough". Again, non-smoker here. Glad to know I'm not the only one dealing with this.
Loading...
I've often wondered about carrier symptoms. My daughter has the most common type of CF, DeltaF508. My non-smoking grandfather died of emphysema. Two of my uncles had such bad asthma as kids they almost died. My sister was constantly getting croup and respiratory infections. I don't have that many symptoms except as a kid I craved, and I mean craved, salt. I would pour it into my hand and eat it straight. After playing and sweating I'd have a salty tasting white powder on my forehead. I still crave salt and eat enough to solidify my blood(!), but always have normal levels.
Loading...
I am a confirmed CF carrier. For my entire adult life, going on 40 years now, I've struggled with thick mucus that causes all sorts of problems, including throat clearing, chronic cough, severe coughing bouts, and various chronic digestive issues, ranging from something like GERD to burning sensations, frequent gas and diarrhea. I do remember a doctor years ago telling me that yes, it is possible for a carrier to express certain "mild" symptoms of CF, but I've seen so, so many doctors over the years for these problems and never been given any kind of solution. Maddening.
Loading...
Ditto for me on very thick, clear(ish) mucus, sometimes stringy or scaly feeling on my tongue. I am 57, with long-term chronic congestion/throat clearing/coughing issues and digestive issues. I am a confirmed carrier, brother died of complications from CF/bilateral lung transplant at age 30. Several people have asked about a support group, but I've seen no replies ... is there one?
Loading...
I have had 5 spontaneous pneumos and my daughter has CF since I am a carrier. I have had consistent issues with gall bladder, pancreas and of course lung issues . I do believe carriers have symptoms of CF but do not know!
Loading...
My lung collapsed 5 times and ended with surgery in 1991. My granddaughter was born and diagnosed with CF and at 5 months old she had a spontaneous pneumothorax. That was my diagnosis with my lung collapse. Whether this is related or not I do not know, but I find being a carrier obviously presents many symptoms of CF that I have not mentioned. Hey
Loading...
My daughter has CF with two copies of the DeltaF508 mutation, so I am definitely a carrier. I've wondered about carrier symptoms. As a child in summer, the skin on my forehead would be whitish where I sweated...salt. I craved salt as a child and would eat a pile of it straight out of my hand. I still crave it. Yet my sodium levels are borderline low. My chloride levels are always low. As long as I can remember, I've had to "clear my throat" off and on all day. When I cough, I always have thick, sometimes solid bits of mucous. I've never felt like I could breath in very far and even as a child got winded and tired way before anybody else during play and other physical activities. I come from a tall family(dad 6ft. 2in), but I'm an average height 5ft. 5in. Chronic iron deficiency makes me wonder about malabsorption. I've never felt well or had any energy. Makes me wonder.
Loading...
My 47 yr old husband is a carrier of DeltaF508 and he's diagnosed with advanced liver disease of unknown origin... Can CF carriers have symptoms?
Loading...