Is it safe to have 16 tooth extraction(s) at once? Without using an anesthesia?

There are a few factors to consider if your dentist is suggesting the extraction of 16 teeth at one time without using general anesthesia:

Type of Anesthesia: If by "without using anesthesia" you mean without general anesthesia, it's possible your dentist may be planning to use local anesthesia. Local anesthesia, such as lidocaine, can numb the specific areas where teeth will be extracted, so you don't feel pain during the procedure but remain awake.
Reason for Extraction: The reason for extracting so many teeth at once may be due to periodontal disease, severe decay, or preparation for dentures or other dental prostheses. Understanding the reason for the extraction can help you understand its necessity.
Safety: The safety of extracting multiple teeth in one session depends on various factors, including your general health, age, and any underlying medical conditions. For many patients, undergoing one larger procedure as opposed to multiple smaller ones may be more convenient and reduce the total healing time. However, it can also be more taxing on the body and may require more post-operative care.
Pain Management: Post-operative pain can be a concern, especially with multiple extractions. Ensure that you have discussed pain management options with your dentist or oral surgeon.
Second Opinion: If you're unsure or uncomfortable with the recommendation, it's always acceptable to seek a second opinion from another dentist or oral surgeon. They can provide additional perspective on the suggested treatment and possible alternatives.
Your Comfort: Some people might be comfortable with the idea of multiple extractions in one session, while others may not be. It's essential to communicate your feelings and concerns with your dentist.