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I started Linzess 6 months ago for bad IBS-C, that I had tried EVERYTHING for, including: fibers natural and commercial (metamucil, citrical, etc.), Mirilax, probiotics, prebiotics, vitamin-c, magnesium, various laxatives in small doses, you name it!

Linzess has been a miracle and I feel much better for the most part, but have been losing weight and did not need to. I have a reduced appetite but am still eating, although I have to watch what I eat very carefully and if I eat too much, it overwhelms my GI system and it will still "shut Down".

I have also developed a cyst in my groin, but not sure if it is at all related to the Linzess.

Anyone else experience this or have any suggestions?

Thanks!

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I also started linzess. I have been losing weight. In 2 weeks I lost 14 lbs. And barely have an appetite. My husband think that I'm trying to lose the weight but I just don't feel hungry. I only eat once a day and that is on the smallest bowl in the house. My last weight in was DEC 29 and before that DEC 8. I lost 14 lbs...no complaints here...by the way I'm diabetic and the Dr tells me that's to much weight loss in short time ..I been losing anywhere from 5 to 7 lbs to fast...
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