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Hello. My Dad is 62 and has been diagnosed with Interstitual Lung Disease. He doesn't have a classic case. He was tested back in August of 2008 and had a PAH of 25 mm Hg. He was told to use Oxygen, but he confesses he didn't feel he needed it / rather just didn't want to wear it. They re-tested him this past April and his PAH is now 88 mm Hg! He just was checked for blood clots and none were found. My question is how bad is that type of a jump in PAH and what could be the reasons for the jump?

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An increase in pulmonary arterial blood pressure from 25 mm Hg to 88 mm Hg in pulmonary arterial hypertension means that the right atrium will have to work a lot harder to get the blood through into the lungs. Sustained pulmonary hypertension can cause right heart failure. Your dad's condition is very serious. You need to persuade your dad to use oxygen even if he doesn't want to.
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He is using oxygen now on a regular basis. But still, what could be the reasons for the jump in the pressure? Is there a possibility of decreasing his PAH?
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Interstitial lung disease causes irreversible scarring of the lungs. The scarring obstructs blood flow to the lungs resulting in pulmonary hypertension. The sharp rise in pulmonary arterial blood pressure may be an indication that the scarring has become much worse. Ultimately, lung transplant may be the only option. High dose coenzyme Q10 (ubiquinone), a powerful antioxidant, may be helpful in slowing the progression of the disease. You may want to give this a try, as your dad really has nothing to lose at this point.
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Here is the update as to my Dad's Echo Report...
Indication of Echo - Dyspney
Technical Quality - BSA @ 2.1 m2 - fair
RV enlarged EDD: 34; RA enlarged size 45 x 59; LA Thrombus - no
LV - NL is checked EDD: 43; LA enlarged siz 43 x 61
Aortic Root NL is checked ADN is not checked 31
Wall Thickness LVH is checked with ASH or NL both not checked at 12 ivs 12 pn
Ejection Fraction 74%
Diastolic Dysfunction checked
Absent checked
LV Thrombus Seen - no is checked
Pericardium - NL is checked
Interatrial Septum - NL is checked
Ventricular Septum - NL is checked

CONCLUSIONS:
1. Normal Left Ventricular Size and Function: EF 75%
2. Concentric LVH with increased BI-ATRIAL and increased Right Ventricular Size
3. Severe Tricuspid Regurgitation with markedly increased PAP and severe pulmonary hypertension.
4. Thickened Aortic and Mitral Valve with normal function.
5. Normal Pulmonic valve function, can not clearly see valve to evaluate structure.
6. Normal pericardium and aorta size, increased inferior vena cava at 2.1 cm
7. Compared to previous Echo (August 2008) Severe Pulmonary Hypertension is now present.

August 2008 25 mm Hg
April 2009 88 mm Hg
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