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I'm a 30+ male diagnosed with treatemnt resistent ADD. Over the past 5 years or so I've tried strattera, ritalin, adderall, wellbutrin, dexedrine and desoxyn with little or no benefit. My longest treatments have been on ritalin and desoxyn (about 6 month each). I've also had behavioral and psych counseling while on meds and off them and tried 4-5 differrent SSRI's (I'm not depresses, but my doctors thought it might help with the ADD or that maybe I was depressed or had dysthymia in addition to, or instead of, the ADD - so we gat them an unsuccessful 8+ wk try for each SSRI)

I stopped all meds about 4months ago, but recently an old friend came to visit and brough some crystal meth with him. I never used any drugs before except prescritption (I did smoke pot twice in my late teens but didn't like it), and I don't drink, so even though it was out of character for me, I did do some with him.

He gave me some to snort and it burned like crazy. After I snorted 3 times (he did more like 5 times) he asked if I was feeling good and I told him I didn't feel much of anything. I tried two more lines, but still I didn't have any response. After a while he brough out a glass pipe and I smoke a 2 times which he told me would make me feel like I was in heaven, but with the exception that I didn't cough like I was dying (like I did when I smoked pot) I didn't get any kind of pleasurable response from the smoking either.

About the only thing I did get was insomnia, which I got from the Adderall and Desoxyn when I took them, but this was much worse and lasted more than 24 hours. About 2 weeks after he left, I took 270mgs of desoxyn left over from before I stopped taking it to see if maybe his crystal meth was really something else. I had the same reaction I did when I did the crystal meth with him, no good feeling and wicked insomnia. All along I never could understand why people would become addicted to ritalin, adderall or desoxyn and I always assumed that it was becasue I was taking less than they do and taking it orally. Now I feel that there maybe a more signaifcant neurochemical difference with me and most others.

Do you have any ideas why I didn't get the kind of pleasurable hit that my friend (who has been using it for almost a year) did? I'm hoping that an answer might point to something which would help with my ADD.

Thank you.

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Please pardon the paraphrasing.

I'm a 34 male also ADD and Also been on Cilert and Ritalin for several years with little no benefit since childhood. I have been depressed much over the years off and on and SSRI's helped only a little maybe but not enough to warrant taking them any longer. Valium and other benzo’s don’t work much for me even though I know people that practically become goofy from 10mg of Valium. I’ve taken up to 40 with no real effect.

At 29yrs old I experimented with elicit drugs. I went 27 years al throughout school with no interest in trying drugs. A friend offered to do Crack Cocaine with me. I did smoke pot but also don't care for the smell or strong smoke. Plus pot just wasn’t my Schtick, I don't drink only except for special occasions.

She explained how to do it with the glass pipe she got her hit then I tried. After she got her hit, she asked why I wasn't feeling high I tried again, with no dramatic response. She said I wasn’t doing it right. We tried a different way with tin foil and a pill bottle but still nothing but she was in a different world.
The only thing I got was heart palpitation. I believe that people with ADD or other neurological problems may not respond to certain prescription or elicit drugs due to the fact the our neurotransmitters are askew.

You wrote:
Do you have any ideas why I didn't get the kind of pleasurable hit that my friend (who has been using it for almost a year) did? I'm hoping that an answer might point to something, which would help with my ADD.

I wont tell what gave me the response you’re looking for because I have a conscience and it almost completely wrecked my life. I’m an addict now. Needless say I successfully found my as you say pleasurable hit. I paid dearly and it certainly didn’t offer any help with the ADD.

Please be safe and don’t look for trouble because it may just find you. Stick with your doctor and don’t give up

Friend
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 Stay away from that crazy sh*t before you get hooked and you are really sorry for ever starting to use it. that sh*t will steal your life from you. I promise!

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Why would anyone bother with "street drugs" when you have equivalent prescription? That baffle's me...

Once I was diagnosed with ADHD and prescribed Adderall, I never craved meth again.

Adderall (meth in past) puts a hold on my 'excessive' drinking.

My reply is a 'knee jerk' reaction, I will think about a better reply if people are still responding and interested in this topic.
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He probley had some bunk dope I used crystal for 6 years and ya sometimes I felt nothing because it was cut.....u coughed of meth smoke? That in and of it self is strange that has never happed 2 me or any one I know when u smoked it once it got hot and u started 2 roll the pipe did a bunch of stuff run from the flame? If so ya it was cut 2 sh*t if u did as much as u say u did u should have been spun out of Ur mind....but a history of the kinda pills Ur on and having ADD if whatever Would make u have a tolerance
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You're right on about the significant difference between and the average person(in terms of neurotransmitters)!

The desoxyn that you had already been taking is actually prescription meth (cool as c**p, right!).

If you didn't have a reaction to the desoxyn, then you should also demonstrate a significant tolerance to the crystal meth.

Do some research on the neurotransmitter dysfunctions associated with meth tolerance, and, by-the-way, the resistant ADD/ADHD diagnosis is merely an idiopathic prognosis. Also, forget the dysrhythmia. You don't have it. You're writing doesn't include the signature marks of the person who lives under perpetual cloud-cover (Yes, I can tell that sort of thing from your writing). No giving up. You just happen to have a really cool under-examined and unclassified type of neurochemical make-up. It's cool to be drug-invincible. Obviously no one will be drugging you to get the truth about the actual meaning of that tattoo on your shoulder!
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genetics - search for articles about narcolepsy and addiction and you'll find that narcoleptics don't get addicted to stimulants.
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I assure you I can help you figure out why amphetamines do not work on you. I am the same way. I do not want to tell you right off the bat what I have before getting your symptoms and history. Then I will tell you why I am the same way as you are describing. Maybe you have the same thing. 

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same with me

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might I add I took my first puff 'meth &slept for 48 hours a relief from my normal hyper state, All I needed for the next 20 Years(a really good nap!) No more needed for now.....
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Could be a few things, but sounds most likely you're (mentally) used to the way amp stimulants make you feel having taken them therapeutically for so long. Also once your body acclimates to high levels of meth your body begins to want it, thus it seems more rewarding when you finally get it. It grows on you the more you do it; kinda clicks in place. That's why more experienced users will seem •happier when doing or having it. Or maybe gods just looking out for you lol.

 

Danger of meth, or any drug is when it does make u •happy in and of its self. People are content w lives going to sh*t and doing horrible things as long as they have their emotional remedy.

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Be glad you didnt because when you do its big waste of life. I didnt either until i smoked it on 3rd time trying. I wish i ran when offered back in 2001. Ive been struggling off and on since. And all i can say is the only thing that helps is cut all ties to past party buddies. Youll be just fine by week 2 . it takes prayer and pot for me. But still hard when struggling to keep secret and not reaching out. I hope you ran or found what Works
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You took 54 pills at one time ? Holy sh*t man.
I'm sorry but this story isn't quite adding up if you ask me. I will eventually figure out whatever it is you aren't telling us
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Sorry I wasn't saying that to you I was commenting on original blog on this page.

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I read somewhere pretty recently how a discovery of how strattera will somehow block and or reverse the ability for metgamphetamine to produce the same effect of dopamine or the amount something like that therefore making it not as pleasurable as before.
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