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Antibiotics represent one of the biggest successes of the modern medicine. There are many stories regarding the possible outcomes of mixing alcohol and antibiotics, but most of them are just myths!
One of the biggest myths is that mixing any antibiotics and alcohol has the potential to cause serious health complications. Although doctors do not advise mixing most medicines with alcohol, only a few medications are actually affected by the combination with alcohol. 

The fact is that antibiotics have different routes of leaving the body. These medications are broken down by the liver, excreted in the urine or pass straight through the gastrointestinal system, after which they end up in the feces. The excretion route determines how long the drugs stay active in the body and how often they need to be taken. What alcohol may do in combination with antibiotics is increase the drugs’ excretion rate or slow down the rate drugs are being broken down. [1]

Alcohol-Medication Interactions

Many medications and not only antibiotics, when combined with alcohol, can cause [2]:

  • increased risk of illness
  • injury
  • death

Some statistics show that alcohol-medication interactions made up at least 25 percent of all emergency room visits.

Incidence of the alcohol-drugs interactions

Over 2,800 prescription drugs are available in the United States today and health experts prescribe 14 billion of them annually. Additionally, there are around 2,000 over-the-counter medications, for which patients do not even need to see a doctor. With 70 percent of the adult population consuming alcohol occasionally and 10 percent drinking daily, some concurrent use of alcohol and prescription or over the counter medications is inevitable. [3]

Although people aged 65 and older make up only 12 percent of the population, they consume 25 to 30 percent of all prescription medications and may be more likely to use them along with alcohol. This puts this age group at particular risk for suffering from the adverse consequences of such combinations. Older people are also more likely to experience medication side effects in comparison to younger people, and these effects tend to get more severe with advancing age.

What Are Antibiotics?

What kind of drugs are antibiotics? These drugs kill or slow the growth of bacteria. They belong to the class of antimicrobials, a larger group which also includes antiviral, antifungal, and anti-parasitic drugs.

Classes of Antibiotics [4]

Aminoglycosides

  • Amikacin
  • Gentamicin
  • Kanamycin
  • Neomycin
  • Netilmicin
  • Streptomycin
  • Tobramycin

Carbacephem

  • Loracarbef

Carbapenems

  • Ertapenem
  • Imipenem/Cilastatin
  • Meropenem

Cephalosporins

  • Cefadroxil
  • Cefazolin
  • Cephalexin
  • Cefamandole
  • Cefoxitin
  • Ceftriaxone
  • Cefepime

Glycopeptides

  • Teicoplanin
  • Vancomycin

Macrolides

  • Azithromycin
  • Clarithromycin
  • Dirithromycin
  • Erythromycin
  • Troleandomycin

Monobactam

  • Aztreonam

Penicillins

  • Amoxicillin
  • Ampicillin
  • Azlocillin
  • Carbenicillin
  • Cloxacillin
  • Dicloxacillin
  • Flucloxacillin
  • Mezlocillin
  • Nafcillin
  • Penicillin
  • Piperacillin
  • Ticarcillin

Polypeptides

  • Bacitracin
  • Colistin
  • Polymyxin B

Quinolones

  • Ciprofloxacin
  • Enoxacin
  • Gatifloxacin
  • Norfloxacin
  • Ofloxacin
  • Trovafloxacin

Sulfonamides

  • Mafenide
  • Prontosil (archaic)
  • Sulfacetamide
  • Sulfamethizole
  • Sulfanilimide (archaic)
  • Sulfasalazine
  • Sulfisoxazole
  • Trimethoprim

Tetracyclines

  • Demeclocycline
  • Doxycycline
  • Tetracycline
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