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Lysergic acid diethylamide, also known as LSD, is one of the most powerful hallucinogenic drugs known. It works by stimulating the centers of the sympathetic nervous system in the brain, causing dilation of the pupils, an increase in body temperature and a rise in the blood-sugar level. It also blocks the effects of serotonin. During the first hour after the ingestion, the user may experience visual changes with extreme changes in mood. The user may also suffer impaired depth and time perception, with distorted perception of the size and shape of objects, movements, color, sound, touch and the user's own body image.
* Mescaline and Psilocybin
These drugs can be isolated from the following natural sources:
o Lysergic acid amide from morning glory seeds,
o Psilocybin from the "magic mushroom", Psilocybe Mexicana.
o Mescaline is isolated from a peyote cactus but it can also be produced synthetically
Psilocybin is from the same chemical family as LSD and their effects are similar. How do these substances work? Well, these molecules fit into the same places as the neuro-transmitters and over-stimulate them, leading to false signals being created. Negative physical symptoms of psilocybin use can include vomiting, muscle weakness, drowsiness, and panic reactions. Frequent use of this drug can result in the development of tolerance. These mushrooms are usually ingested orally, but can also be brewed in a tea or added to food to mask the bitter flavor. Once ingested, psilocybin is broken down in the user's body to produce psilocyn, another hallucinogenic substance.
Serotonin neurotransmitter that is normally found in several places in our body. Some of the most common localizations are:
o Cardiovascular tissue,
o Endothelial cells,
o Blood cells, and
o The central nervous system.
The effects of serotonin are still unknown but experts believe that it is causing similar effects to our body like all the other hallucinogenic drugs. So, in a way, it represents a kind of a personal body hallucinogen.